0000000000807294

AUTHOR

Ramos Verde Ana

showing 2 related works from this author

Cytomegalovirus prevention strategies in seropositive kidney transplant recipients: an insight into current clinical practice

2015

Producción Científica

AdultMalemedicine.medical_specialtyRiñones - TrasplanteCongenital cytomegalovirus infectionCytomegaloviruskidney transplantationSIDA (Enfermedad)Kaplan-Meier EstimateDiseaseAntiviral AgentsAsymptomaticRisk FactorsInternal medicineseropositive recipientpreemptive therapymedicineHumansValganciclovirProspective StudiesRenal InsufficiencyPropensity ScoreGanciclovircytomegalovirusKidney transplantationAgedProportional Hazards ModelsTransplantation3205.06 Nefrologíabusiness.industryProportional hazards modelIncidenceIncidence (epidemiology)antiviral prophylaxisMiddle Agedmedicine.diseaseKidney TransplantationDiscontinuationSurgerymulticenter studySpainCytomegalovirus InfectionsPropensity score matchingFemalemedicine.symptombusinessImmunosuppressive AgentsGlomerular Filtration Rate
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Association Between Individual and Combined SNPs in Genes Related to Innate Immunity and Incidence of CMV Infection in Seropositive Kidney Transplant…

2014

In this study, we assessed the association between single-nucleotide polymorphisms (SNPs) in seven candidate genes involved in orchestrating the immune response against cytomegalovirus (CMV) and the 12-month incidence of CMV infection in 315 CMV-seropositive kidney transplant (KT) recipients. Patients were managed either by antiviral prophylaxis or preemptive therapy. CMV infection occurred in 140 patients (44.4%), including 13 episodes of disease. After adjusting for various clinical covariates, patients harboring T-allele genotypes of interleukin-28B (IL28B) (rs12979860) SNP had lower incidence of CMV infection (adjusted hazard ratio [aHR]: 0.66; 95% confidence interval [CI]: 0.46-0.96; p…

AdultMaleCandidate geneGenotypeReceptors Cell SurfaceSingle-nucleotide polymorphismDiseasePolymorphism Single NucleotideImmune systemGenotypeOdds RatioHumansImmunology and AllergyMedicineSNPLectins C-TypePharmacology (medical)Prospective StudiesAllelesAgedProportional Hazards ModelsTransplantationbusiness.industryIncidenceInterleukinsHazard ratioTLR9Middle AgedKidney TransplantationImmunity InnateTransplant RecipientsCytomegalovirus InfectionsImmunologyKidney Failure ChronicFemaleInterferonsbusinessCell Adhesion MoleculesAmerican Journal of Transplantation
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