0000000000807997

AUTHOR

James M. Byrne

0000-0002-4399-7336

showing 3 related works from this author

Bio-imaging with the helium-ion microscope: A review

2021

Scanning helium-ion microscopy (HIM) is an imaging technique with sub-nanometre resolution and is a powerful tool to resolve some of the tiniest structures in biology. In many aspects, the HIM resembles a field-emission scanning electron microscope (FE-SEM), but the use of helium ions rather than electrons provides several advantages, including higher surface sensitivity, larger depth of field, and a straightforward charge-compensating electron flood gun, which enables imaging of non-conductive samples, rendering HIM a promising high-resolution imaging technique for biological samples. Starting with studies focused on medical research, the last decade has seen some particularly spectacular …

Materials scienceBiological objectshimIonofluorescenseGeneral Physics and AstronomyBio-imagingNanotechnology02 engineering and technologyReviewmikroskopialcsh:Chemical technologylcsh:Technology03 medical and health sciencesBiological specimenBio imagingHelium-ion microscopyhelium-ion microscopyMicroscopyNanotechnologyGeneral Materials ScienceHigh resolutionlcsh:TP1-1185Depth of fieldElectrical and Electronic Engineeringlcsh:Science030304 developmental biology0303 health sciencesFlood gunhigh resolutionlcsh:THIMionofluorescense021001 nanoscience & nanotechnologyBiological materialslcsh:QC1-999him-simsSecondary ion mass spectrometryflood gunNanosciencekuvantaminenbio-imagingvirologiaHIM-SIMSlcsh:Qmikrobiologia0210 nano-technologyField ion microscopelcsh:PhysicssolubiologiaBeilstein Journal of Nanotechnology
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Abiotic versus biotic iron mineral transformation studied by a miniaturized backscattering Mössbauer spectrometer (MIMOS II), X-ray diffraction and R…

2017

Abstract Searching for biomarkers or signatures of microbial transformations of minerals is a critical aspect for determining how life evolved on Earth, and whether or not life may have existed in other planets, including Mars. In order to solve such questions, several missions to Mars have sought to determine the geochemistry and mineralogy on the Martian surface. This research includes the two miniaturized Mossbauer spectrometers (MIMOS II) on board the Mars Exploration Rovers Spirit and Opportunity, which have detected a variety of iron minerals on Mars, including magnetite (Fe2+Fe3+2O4) and goethite (α-FeO(OH)). On Earth, both minerals can derive from microbiological activity (e.g. thro…

GoethiteMineral010504 meteorology & atmospheric sciencesChemistryMineralogyAstronomy and AstrophysicsContext (language use)Mars Exploration Program01 natural scienceschemistry.chemical_compoundFerrihydriteSpace and Planetary ScienceMartian surfacevisual_art0103 physical sciencesMössbauer spectroscopyvisual_art.visual_art_medium010303 astronomy & astrophysics0105 earth and related environmental sciencesMagnetiteIcarus
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Imaging and Ion-Beam Milling of Biological Specimens with the Helium-Ion Microscope

2021

Biological specimenMaterials sciencechemistryIon beamAnalytical chemistrychemistry.chemical_elementInstrumentationHeliumField ion microscopeMicroscopy and Microanalysis
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