0000000000809330
AUTHOR
Israel Morales-sanchez
Myoepithelial cells are the main component in pleomorphic adenomas?
Objective: The aim of this study was to quantify by immunohistochemistry the number of myoepithelial cells (MyECs) in pleomorphic adenomas (PAs). Material and methods: We retrieved the paraffin cubes of 27 PAs, new slides were done and they were stained with anti-S100 protein antibody. The amount of S-100 protein positive cells was quantified, their morphology was recorded and comparison among MyEC number with age, gender and involved gland were also done. Results: With S-100 protein, MyECs in normal salivary gland tissue were seen surrounding the ductual structures only. In the analysed PAs a mean of 27.4% of the neoplastic cells were positive to the antibody. With the exception of one PA,…
Toxicity test of a dental commercial composite in rats.
Objective: The aim of this study was to determine the 90-day subchronic toxicity of one triethylene glycol dimethacrylate containing composite (MEDENTAL Light-Cure Composite™) orally administered to rats according to OECD no. 48 guidelines and the requirements specified in the International Organization for Standardization 10993-11. Study design: The composite was administered orally to Wistar rats during 90 days and they were observed to determine changes in their behavior, eye and skin signs and other attitudes such as aggressiveness, posture, walking and response to handling. After 90 days they were sacrificed to determine blood alterations, special hematological tests were done and hist…