0000000000815392
AUTHOR
Martin Schroeder
showing 2 related works from this author
Cost-efficient strategies to preserve dead wood-dependent species in a managed forest landscape
2016
Negative consequences of intensive forest management on biodiversity are often mitigated by setting aside old forest, but alternative strategies have been suggested. We have compared using simulations the consequences of two of these alternatives setting aside young forests or extending rotation periods - to that of current practice in managed boreal forest In all scenarios we applied a constant conservation budget and predicted forest development and harvesting over 200 years. As a proxy for biodiversity conservation, we projected the extinction risk of a dead wood-dependent beetle, Diacanthous undulatus, in a 50 km(2) landscape in central Sweden, using a colonization-extinction model. Dur…
Safety and efficacy of outpatient treatment with CPT-11 plus bolus folinic acid/5-fluorouracil as first-line chemotherapy for metastatic colorectal c…
2003
The combination of irinotecan (CPT-11), bolus 5-fluorouracil (5-FU) and folinic acid (FA) (Saltz regimen) has recently been questioned as first-line chemotherapy for metastatic colorectal cancer after high early death rates due to gastrointestinal and thromboembolic events were reported in two US trials. Therefore, we carefully evaluated the safety and efficacy of this regimen, with high value placed on the management of delayed diarrhea. Forty-six patients with metastatic colorectal cancer received this first-line treatment in nine German outpatient clinics. Dose reductions were mandatory from the first cycle in case of toxicity grade2. Chemotherapy was administered only to diarrhea-free p…