Author: Darlene Santiago

0000000000815487

AUTHOR

Darlene Santiago

0000-0001-5802-9381

showing 1 related works from this author

Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder …

2020

Background: The aim of this analysis was to characterize the pharmacokinetics (PK) of sublingual buprenorphine (BUP) and its metabolites (buprenorphine glucuronide

PopulationCmaxbuprenorphine/naloxone sublingual filmlcsh:RS1-441Pharmaceutical SciencePharmacology030226 pharmacology & pharmacyArticlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePharmacokineticspopulation pharmacokineticsNaloxonemedicine030212 general & internal medicineDosingNorbuprenorphinePuerto Ricanseducationeducation.field_of_studyopioid use disorder (OUD)business.industrypopPKchemistryGlucuronidebusinessSuboxonepharmacokineticsmedicine.drugBuprenorphinecompartmental modelingPharmaceutics

researchProduct

PEPhysical Sciences and Engineering
- PE2Fundamental Constituents of Matter
  - PE2_1Theory of fundamental interactions
  - PE2_2 Phenomenology of fundamental interactions
  - PE2_3Experimental particle physics with accelerators
  - PE2_4Experimental particle physics without accelerators
  - PE2_6Nuclear, hadron and heavy ion physics
  - PE2_8Gas and plasma physics
  - PE2_5Classical and quantum physics of gravitational interactions
  - PE2_7Nuclear and particle astrophysics
  - PE2_9 Electromagnetism
  - PE2_10Atomic, molecular physics
  - PE2_11Ultra-cold atoms and molecules
  - PE2_18Equilibrium and non-equilibrium statistical mechanics: steady states and dynamics
  - PE2_14Lasers, ultra-short lasers and laser physics
  - PE2_17Metrology and measurement
  - PE2_16Non-linear physics
  - PE2_12Optics, non-linear optics and nano-optics
  - PE2_13Quantum optics and quantum information
  - PE2_15Thermodynamics
- PE1Mathematics
  - PE1_1Logic and foundations
  - PE1_6Geometry and global analysis
  - PE1_8Analysis
  - PE1_7Topology
  - PE1_9Operator algebras and functional analysis
  - PE1_10ODE and dynamical systems
  - PE1_12Mathematical physics
  - PE1_11Theoretical aspects of partial differential equations
  - PE1_13Probability
  - PE1_14Mathematical statistics
  - PE1_15Generic statistical methodology and modelling
  - PE1_4 Algebraic and complex geometry
  - PE1_19Scientific computing and data processing
  - PE1_2Algebra
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  - PE1_21Application of mathematics in sciences
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  - PE1_5Lie groups, Lie algebras
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  - PE1_3Number theory
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  - PE3_1Structure of solids, material growth and characterisation
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  - PE10_18Cryosphere, dynamics of snow and ice cover, sea ice, permafrosts and ice sheets
  - PE10_20Geohazards
  - PE10_19Planetary geology and geophysics
  - PE10_21Earth system modelling and interactions
  - PE10_14Earth observations from space/remote sensing
  - PE10_11Geochemistry, cosmochemistry, crystal chemistry, isotope geochemistry, thermodynamics
  - PE10_13Physical geography, geomorphology
  - PE10_12Sedimentology, soil science, palaeontology, earth evolution
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  - PE11_2Engineering of metals and alloys
  - PE11_1Engineering of biomaterials, biomimetic, bioinspired and bio-enabled materials
  - PE11_3Engineering of ceramics and glasses
  - PE11_4Engineering of polymers and plastics
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  - PE11_6Engineering of carbon materials
  - PE11_7Engineering of metal oxides
  - PE11_8Engineering of alternative established or emergent materials
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  - PE11_10Soft materials engineering, e.g. gels, foams, colloids
  - PE11_11Porous materials engineering, e.g. covalent-organic, metal-organic, porous aromatic frameworks
  - PE11_12Semi-conducting and magnetic materials engineering
  - PE11_13Metamaterials engineering
  - PE11_14Computational methods for materials engineering
LSLife Sciences
- LS1Molecules of Life: Biological Mechanisms, Structures and Functions
  - LS1_2Biochemistry
  - LS1_1Macromolecular complexes including interactions involving nucleic acids, proteins, lipids and carbohydrates
  - LS1_3DNA and RNA biology
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  - LS1_13Early translational research and drug design
  - LS1_14Innovative methods and modelling in molecular, structural and synthetic biology
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  - LS1_9Molecular mechanisms of signalling processes
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- LS2Integrative Biology: from Genes and Genomes to Systems
  - LS2_1Genetics
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  - LS2_16Innovative methods and modelling in integrative biology
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  - LS4_1Organ and tissue physiology and pathophysiology
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  - LS4_6Microbiome and host physiology
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  - LS3_7Mechanobiology of cells, tissues and organs
  - LS3_8Embryogenesis, pattern formation, morphogenesis
  - LS3_9Cell differentiation, formation of tissues and organs
  - LS3_10Developmental genetics
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  - LS3_3Cell behaviour, including control of cell shape, cell migration
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  - LS3_17Theoretical modelling in cellular, developmental and regenerative biology
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  - LS3_1Cell cycle, cell division and growth
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- LS5Neuroscience and Disorders of the Nervous System
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  - LS5_4Neural stem cells
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  - LS9_7Environmental biotechnology and bioengineering
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  - LS9_1Bioengineering for synthetic and chemical biology
SHSocial Sciences and Humanities
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  - SH5_4Philology; text and image studies
  - SH5_1Classics, ancient literature
  - SH5_5Palaeography and codicology
  - SH5_3Book studies
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  - SH5_8Metaphysics, philosophical anthropology; aesthetics
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  - SH5_10History of philosophy
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  - SH7_8Land use and planning
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  - SH8_1Kinship; diversity and identities, gender, interethnic relations
  - SH8_2Religious studies, ritual; symbolic representation
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  - SH8_5History of art and of architecture
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  - SH8_7Music and musicology; history of music
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