Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico

6533b835fe1ef96bd129ec51

RESEARCH PRODUCT

Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder in Puerto Rico

Jorge Duconge Victor Mangas Sanjuan Victor Mangas-sanjuan Darlene Santiago Kyle Melin Raman Venkataramanan Wenchen Zhao

subject

Population Cmax buprenorphine/naloxone sublingual film lcsh:RS1-441 Pharmaceutical Science Pharmacology 030226 pharmacology & pharmacy Article lcsh:Pharmacy and materia medica 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Pharmacokinetics population pharmacokinetics Naloxone medicine 030212 general & internal medicine Dosing Norbuprenorphine Puerto Ricans education education.field_of_study opioid use disorder (OUD)business.industry popPK chemistry Glucuronide business Suboxone pharmacokinetics medicine.drug Buprenorphine compartmental modeling

description

Background: The aim of this analysis was to characterize the pharmacokinetics (PK) of sublingual buprenorphine (BUP) and its metabolites (buprenorphine glucuronide

year	journal	country	edition	language
2020-12-18	Pharmaceutics

10.3390/pharmaceutics12121226 http://europepmc.org/articles/PMC7766849

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