Search results for "Norbuprenorphine"

showing 2 items of 2 documents

Development of a new multi-analyte assay for the simultaneous detection of opioids in serum and other body fluids using liquid chromatography-tandem …

2015

Abstract A liquid chromatography–tandem mass spectrometry method using electrospray ionization in positive ionization mode was developed for the simultaneous detection of multiple opioid-type drugs in plasma. The presented assay allows the quantitative determination of alfentanil, buprenorphine, codeine, desomorphine, dextromethorphan, dextrorphan, dihydrocodeine, dihydromorphine, ethylmorphine, fentanyl, hydrocodone, hydromorphone, methadone, morphine, naloxone, naltrexone, oxycodone, oxymorphone, pentazocine, pethidine, pholcodine, piritramide, remifentanil, sufentanil, and tramadol as well as the metabolites 6-monoacetylmorphine, bisnortilidine, morphine-3-glucuronide, morphine-6-glucuro…

ChromatographyChemistryClinical BiochemistryCodeineReproducibility of ResultsCell BiologyGeneral MedicineEthylmorphineBiochemistryDihydrocodeineAnalytical ChemistryTriple quadrupole mass spectrometerBody FluidsAnalgesics Opioidchemistry.chemical_compoundLiquid chromatography–mass spectrometryLimit of DetectionTandem Mass SpectrometryIntensive caremedicineMorphineHumansNorbuprenorphinemedicine.drugChromatography LiquidJournal of chromatography. B, Analytical technologies in the biomedical and life sciences
researchProduct

Pharmacokinetic Characterization and External Evaluation of a Quantitative Framework of Sublingual Buprenorphine in Patients with an Opioid Disorder …

2020

Background: The aim of this analysis was to characterize the pharmacokinetics (PK) of sublingual buprenorphine (BUP) and its metabolites (buprenorphine glucuronide

PopulationCmaxbuprenorphine/naloxone sublingual filmlcsh:RS1-441Pharmaceutical SciencePharmacology030226 pharmacology & pharmacyArticlelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePharmacokineticspopulation pharmacokineticsNaloxonemedicine030212 general & internal medicineDosingNorbuprenorphinePuerto Ricanseducationeducation.field_of_studyopioid use disorder (OUD)business.industrypopPKchemistryGlucuronidebusinessSuboxonepharmacokineticsmedicine.drugBuprenorphinecompartmental modelingPharmaceutics
researchProduct