0000000000820049
AUTHOR
Sarmīte Kupča
Aptaukošanās bērniem Latvijā un ar to saistītie riska faktori
Elektroniskā versija nesatur pielikumus
Inflammatory Cytokine IFNγ, IL-6, and IL-10 Association with Childhood Obesity
Abstract Childhood obesity carries a high risk of serious life-threatening cardiometabolic diseases in adulthood, which are associated with low-grade inflammation. The aim of the present study was to measure serum cytokine concentrations in obese children recruited during endocrinology consultations and compared to lean control the results. Blood serum concentrations of interferon gamma (IFNγ), IL-1β, Interleukin 6 IL-6, IL-10, and TNF-α were analysed applying Luminex xMap technology with Millipore reagent kits. Statistical analyses were performed using t-test comparisons and Spearman correlations. Obese children had highly significant increased levels of circulating IFNγ (p < 0.0001), I…