0000000000821587

AUTHOR

Fernando Goñi-irigoyen

0000-0001-7903-6409

showing 3 related works from this author

Organochlorine Compounds and Ultrasound Measurements of Fetal Growth in the INMA Cohort (Spain)

2014

This study was funded by grants from the EU (European Union): NEWGENERIS FP6-2003- Food-3-A-016320, FP7-ENV-2011 cod 282957, HEALTH.2010.2.4.5-1; and by grants from Spain: Instituto de Salud Carlos III (Red INMA G03/176, CB06/02/0031, and FIS-FEDER PI03/1615, PI04/1509, PI04/1112, PI04/1931, PI04/2018, PI04/1436, PI05/1079, PI05/1052, PI06/1213, PI07/0314, PI08/1151, PI09/02647, PI09/02311, PI11/01007, PI11/02591, PI11/02038, PI13/1944, PI13/02429, PI14/0891, PI14/1687, and Miguel Servet CP11/00178 and CP13/00054), Conselleria de Sanitat Generalitat Valenciana, Generalitat de Catalunya (CIRIT 1999SGR 00241), Diputación Foral de Guipúzcoa (DFG/004), Departamento de Sanidad y Consumo Gobierno…

Adultmedicine.medical_specialtyHealth Toxicology and MutagenesisPhysiologyUltrasonography PrenatalFetal Developmentchemistry.chemical_compoundPregnancyInternal medicinemedicineHydrocarbons ChlorinatedHumansFetusPregnancybusiness.industryUltrasoundPublic Health Environmental and Occupational HealthPolychlorinated biphenylHexachlorobenzeneAnthropometrymedicine.disease3. Good healthEndocrinologychemistryMaternal ExposureSpainCohortChildren's HealthGestationFemalebusiness
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Association between exposure to organochlorine compounds and maternal thyroid status: Role of the iodothyronine deiodinase 1 gene.

2017

Introduction: Exposure to organochlorine compounds (OCs) may interfere with thyroid hormone (TH) homeostasis. The disruption of the deiodinase (DIO) enzymes has been proposed as a mechanism of action. Aim: To evaluate the association between exposure to OCs and TH status in pregnant women, as well as to explore the role of genetic variations in the DIO1 and DIO2 genes. Methods: The study population (n = 1128) was composed of pregnant women who participated in the INMA Project (Spain, 2003–2006). Hexachlorobenzene (HCB), 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene (4,4´-DDE), b-hexachlorocyclohexane (b-HCH), polychlorobiphenyl (PCB) congeners 138, 153 and 180, thyroid stimulating hormone (T…

Adultmedicine.medical_specialtyDeiodinaseDIO2Thyrotropin010501 environmental sciences01 natural sciencesIodide Peroxidase03 medical and health sciences0302 clinical medicineThyroid-stimulating hormonePregnancyInternal medicinemedicineHydrocarbons ChlorinatedHumans030212 general & internal medicineDeiodinase enzymeslcsh:Environmental sciences0105 earth and related environmental sciencesGeneral Environmental Sciencelcsh:GE1-350ThyroidPregnancyTriiodothyroninebiologyChemistryThyroidOrganochlorine compoundsFetal developmentmedicine.diseaseDietPregnancy Trimester FirstThyroxinemedicine.anatomical_structureEndocrinologySpainbiology.proteinGestationTriiodothyronineFemaleHormoneEnvironment international
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Prenatal exposure to endocrine disrupting chemicals and risk of being born small for gestational age: Pooled analysis of seven European birth cohorts

2018

Background and aims: There is evidence that endocrine disrupting chemicals (EDCs) have developmental effects at environmental concentrations. We investigated whether some EDCs are associated with the adverse birth outcome Small for Gestational Age (SGA). Methods: We used PCB 153, p,p'-DDE, HCB, PFOS and PFOA measured in maternal, cord blood or breast milk samples of 5446 mother-child pairs (subset of 693 for the perfluorinated compounds) from seven European birth cohorts (1997–2012). SGA infants were those with birth weight below the 10th percentile for the norms defined by gestational age, country and infant's sex. We modelled the association between measured or estimated cord serum EDC co…

0301 basic medicineMalemedicine.medical_specialtyBirth weight010501 environmental sciencesBreast milkEndocrine Disruptors01 natural sciencesPooled analysis03 medical and health sciencesSDG 3 - Good Health and Well-beingInterquartile rangePregnancyMedicine[SDV.EE.SANT] Life Sciences [q-bio]/Ecology environment/HealthHumansBiologylcsh:Environmental sciences0105 earth and related environmental sciencesGeneral Environmental Science2. Zero hungerlcsh:GE1-350[SDV.EE.SANT]Life Sciences [q-bio]/Ecology environment/HealthPregnancyMilk Humanbusiness.industryObstetricsSmokingInfant NewbornGestational ageEnvironmental exposureOdds ratioEndocrine disrupting chemicals (EDCs)Infant Low Birth Weightmedicine.diseaseFetal Blood3. Good healthChemistrySmall for gestational age (SGA)030104 developmental biology[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieMaternal ExposurePrenatal Exposure Delayed EffectsSmall for gestational age/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingFemale[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologiebusiness
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