0000000000822115
AUTHOR
Isabelle Kermarrec
showing 4 related works from this author
Visceral fat area as a new independent predictive factor of survival in patients with metastatic renal cell carcinoma treated with antiangiogenic age…
2011
Abstract Purpose. A better identification of patients who are more likely to benefit from vascular endothelial growth factor–targeted therapy is warranted in metastatic renal cell carcinoma (mRCC). As adipose tissue releases angiogenic factors, we determined whether parameters such as visceral fat area (VFA) were associated with outcome in these patients. Experimental Design. In 113 patients with mRCC who received antiangiogenic agents (bevacizumab, sunitinib, or sorafenib) (n = 64) or cytokines (n = 49) as first-line treatment, we used computed tomography to measure VFA and subcutaneous fat area (SFA). We evaluated associations linking body mass index (BMI), SFA, and VFA to time to progres…
Le robot améliore-t-il la prostatectomie totale laparoscopique dans les cas complexes ?
2010
Resume La prostatectomie totale est le traitement de reference du cancer de prostate de l’homme jeune. Mais dans les cas difficiles, les patients peuvent etre orientes vers une autre option therapeutique. Objectif Evaluation de la qualite de l’anastomose dans les cas complexes de chirurgie comparant la voie laparoscopique PTL a la voie laparoscopique assistee du robot PTLR. Materiel Trois cent quatre-vingt dix-sept patients ont ete operes de mars 2004 a aout 2009, 176 PTL et 221 PTLR de maniere consecutive par un meme chirurgien. Les antecedents pouvant compliquer le geste chirurgical ont ete analyses : volume prostatique superieur a 80 cc, antecedent de cure de hernie inguinale avec prothe…
Transcatheter embolization of a renal artery pseudoaneurysm after open partial nephrectomy.
2011
Twelve days after an open partial nephrectomy, a 31-year-old man was re-admitted urgently for acute lumbar pain. An emergent helical computed tomography scan with intravenous contrast revealed a 3-cm renal artery pseudoaneurysm at the site of the partial nephrectomy, which was responsible for a large perirenal hematoma. Transarterial hyperselective embolization successfully occluded the pseudoaneurysm with less than 1 mL of N-butyl-2-cyanoacrylate, an embolizing agent less costly than coils. The kidney parenchyma was fully preserved.
Metronomic oral cyclophosphamide prednisolone chemotherapy is an effective treatment for metastatic hormone-refractory prostate cancer after docetaxe…
2010
There is currently no standard of treatment for patients with hormone refractory prostate cancer (HRPC) after failure of docetaxel-based chemotherapy. The purpose of this study was to assess the anticancer activity and tolerance of metronomic cyclophosphamide prednisolone combination in this setting.From 2005 to 2010, patients with HRPC who failed at least docetaxel-based chemotherapy were proposed metronomic cyclophosphamide-prednisolone regimen, and were prospectively registered. Twenty-three patients received 50 mg cyclophosphamide and 10 mg prednisolone per os daily until disease progression. Treatment tolerance and efficacy on PSA decrease and pain were studied.Metronomic cyclophospham…