ChemInform Abstract: Synthesis of 5-Substituted 2,3-Dihydrobenzofurans in a One-Pot Oxidation/Cyclization Reaction.

The oxidation of N-protected p-aminophenol derivatives to quinone imides is combined with cycloaddition towards azadiene (II) in a one-pot reaction to give dihydrobenzofuran derivatives in moderate to good yields.

[3+2] versus [4+2] cycloadditions of quinone monoimide with azadienes: a Lewis acid free access to 5-amino-2,3-dihydrobenzofuranes

Synthesis of 5-substituted 2,3-dihydrobenzofurans in a one-pot oxidation/cyclization reaction

Variously substituted 2,3-dihydrobenzofurans have been synthesized according to a sequential one-pot oxidation/cyclization procedure between para-aminophenol derivatives and an azadiene. Variously substituted 2,3-dihydrobenzofurans have been synthesized according to a sequential one-pot oxidation/cyclization procedure between para-aminophenol derivatives and an azadiene. © 2011 Elsevier Ltd. All rights reserved.