0000000000826392

AUTHOR

Andrea Amaducci

showing 3 related works from this author

Haemodynamic predictors of a penetrating atherosclerotic ulcer rupture using fluid-structure interaction analysis

2013

We present preliminary data on the flow-induced haemodynamic and structural loads exerted on a penetrating atherosclerotic aortic ulcer (PAU). Specifically, one-way fluid-structure interaction analysis was performed on the aortic model reconstructed from a 66-year-old male patient with a PAU that evolved into an intramural haematoma and rupture of the thoracic aorta. The results show that elevated blood pressure (117 mmHg) and low flow velocity at the aortic wall (0.15 m/s(2)) occurred in the region of the PAU. We also found a low value of time-averaged wall shear stress (1.24 N/m(2)) and a high value of the temporal oscillation in the wall shear stress (oscillatory shear index = 0.13) in t…

Malemedicine.medical_treatmentHemodynamicsAorta ThoracicMedicineThoracic aortaHematomamedicine.diagnostic_testEndovascular ProceduresModels CardiovascularSettore ING-IND/34 - Bioingegneria IndustrialeAnatomyTreatment OutcomeAtherosclerosiCardiologyWall shear streCardiology and Cardiovascular MedicineBrief CommunicationsBlood Flow VelocityHumanPulmonary and Respiratory Medicinemedicine.medical_specialtyAortographyAortic RuptureAortic DiseasesAortographyBlood Vessel Prosthesis ImplantationSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchinePenetrating atherosclerotic ulcerPenetrating atherosclerotic ulcerInternal medicinemedicine.arteryFluid-structure interactionShear stressHumansArterial PressureComputer SimulationHemodynamicAortic ruptureUlcerAgedEndovascular Procedurebusiness.industryHemodynamicsStentmedicine.diseaseAtherosclerosisAortic DiseaseBlood pressureRegional Blood FlowSurgeryStress MechanicalbusinessTomography X-Ray Computed
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Computational fluid dynamics simulation to evaluate aortic coarctation gradient with contrast-enhanced CT

2014

Coarctation of aorta (CoA) is a narrowing of the aorta leading to a pressure gradient (Delta P) across the coarctation, increased afterload and reduced peripheral perfusion pressures. Indication to invasive treatment is based on values of maximal (systolic) trans-coarctation Delta P. A computational fluid dynamic (CFD) approach is herein presented for the non-invasive haemodynamic assessment of Delta P across CoA. Patient-specific CFD simulations were created from contrast-enhanced computed tomography (CT) and appropriate flow boundary conditions. Computed Delta P was validated with invasive intravascular trans-CoA pressure measurements. Haemodynamic indices, including pressure loss coeffic…

medicine.medical_specialtyBiomedical EngineeringHemodynamicsBioengineeringComputational fluid dynamicscontrast-enhanced computed tomographylaw.inventioncomputational fluid dynamicSettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineAfterloadlawmedicine.arteryInternal medicinemedicineShear stressPressure gradientPressure dropAortabusiness.industryChemistrycoarctation of aortapressure gradientGeneral MedicineComputer Science ApplicationsHuman-Computer InteractionPressure measurementCardiologybusinessComputer Methods in Biomechanics and Biomedical Engineering
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Predicting Outcome of Aortic Dissection with Patent False Lumen by Computational Flow Analysis

2014

Although Type B aortic dissection (AoD) has better in-hospital survival than Type A AoD, the short- and long term outcome for patients remains challenging, with 50–80% deaths at 5-years. Dissection-related complications include rapid aortic expansion, impending rupture, and malperfusion syndromes. We aimed to assess hemodynamic implications of patients with patent false lumen (FL) of dissected aorta. Computational fluid dynamic analyses were performed on patient-specific aortic geometries reconstructed from computed tomography scans of 25 patients with AoDs, who were admitted in our hospital from 2007 to 2013. We used the development of acute complications and chronic aneurysmal evolution a…

Aortic dissectionAortamedicine.medical_specialtyFlowbusiness.industryBiomedical EngineeringFalse LumenHemodynamicsBlood flowmedicine.diseaseType B Aortic DissectionSurgerySettore ING-IND/14 - Progettazione Meccanica E Costruzione Di MacchineBlood pressuremedicine.arteryInternal medicineLinear regressionmedicineCardiologyTearsCFDCardiology and Cardiovascular MedicineAdverse effectbusinessCardiovascular Engineering and Technology
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