0000000000843860
AUTHOR
Marie Dumont
CENP-A Is Dispensable for Mitotic Centromere Function after Initial Centromere/Kinetochore Assembly
SummaryHuman centromeres are defined by chromatin containing the histone H3 variant CENP-A assembled onto repetitive alphoid DNA sequences. By inducing rapid, complete degradation of endogenous CENP-A, we now demonstrate that once the first steps of centromere assembly have been completed in G1/S, continued CENP-A binding is not required for maintaining kinetochore attachment to centromeres or for centromere function in the next mitosis. Degradation of CENP-A prior to kinetochore assembly is found to block deposition of CENP-C and CENP-N, but not CENP-T, thereby producing defective kinetochores and failure of chromosome segregation. Without the continuing presence of CENP-A, CENP-B binding …
Using Optical and Thermal Data for Tracking Snowmelt Processes in Alpine Area
Alpine catchments represent a fundamental reservoir of fresh water at midlatitude. Remote sensing offers the opportunity to estimate snow properties in the optical, thermal and microwave domains. In particular, the possibility to estimate snow density from remote sensing is relevant and still represents a great challenge for the remote sensing scientific community. Since changes of snow density and liquid water content occur continuously in the snowpack, spatial and temporal patterns of optical and thermal data can give information about snowmelt processes. The main goal of this study is to evaluate if snow thermal inertia can be an indicator of snowmelt processes and to evaluate its relati…
Introducing Thermal Inertia for Monitoring Snowmelt Processes With Remote Sensing
Thermal inertia has been successfully used in remote sensing applications that span from geology, geomorphology to hydrology. In this paper, we propose the use of thermal inertia for describing snow dynamics. Two different formulations of thermal inertia were tested using experimental and simulated data related to snowpack dynamics. Experimental data were acquired between 2012 and 2017 from an automatic weather station located in the western Italian Alps at 2,160 m. Simulations were obtained using the one‐dimensional multilayer Crocus model. Results provided evidences that snowmelt phases can be recognized, and average snowpack density can be estimated reasonably well from thermal inertia o…