0000000000849283
AUTHOR
Stéphane Avril
showing 2 related works from this author
Patient-specific computational evaluation of stiffness distribution in ascending thoracic aortic aneurysm
2021
Quantifying local aortic stiffness properties in vivo is acknowledged as essential to assess the severity of an ascending thoracic aortic aneurysm (ATAA). Recently, the LESI (local extensional stiffness identification) methodology has been established to quantify non-invasively local stiffness properties of ATAAs using electrocardiographic-gated computed tomography (ECG-gated CT) scans. The aim of the current study was to determine the most sensitive markers of local ATAA stiffness estimation with the hypothesis that direct measures of local ATAA stiffness could better detect the high-risk patients. A cohort of 30 patients (12 BAV and 18 TAV) referred for aortic size evaluation by ECG-gated…
In Vitro Measurement of Strain Localization Preceding Dissection of the Aortic Wall Subjected to Radial Tension
2020
AbstractBackgroundAortic dissection (AD) is a common pathology and challenging clinical problem. A better understanding of the biomechanical effects preceding its initiation is essential for predicting adverse events on a patient-specific basis. Moreover, the predictability of patient-specific biomechanics-based computational models is hampered by uncertainty about boundary conditions and material properties.ObjectivePredisposition of thoracic aortic aneurysms (TAA) to ADs can be related to the degradation of biomechanically important constituents in the aortic wall of TAAs. The goal of the present study is to develop a new methodology to measure strain fields in aortic tissues subjected to…