0000000000851010

AUTHOR

L. Berzina

showing 2 related works from this author

Microsatellite allele 5.1 of major histocompatibility complex class I chain related gene A (MIC-A) is increased among non-insulin dependent diabetes …

2000

Geneticsbiologybusiness.industryEndocrinology Diabetes and MetabolismNon insulin dependent diabetes mellitusGeneral Medicinemedicine.diseaseMajor histocompatibility complexEastern indiaEndocrinologyDiabetes mellitusInternal Medicinemedicinebiology.proteinMicrosatelliteRelated geneAllelebusinessDiabetes Research and Clinical Practice
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Microsatellite allele A5.1 of MHC class I chain-related gene A is associated with latent autoimmune diabetes in adults in Latvia.

2006

NIDDM is one of the most common forms of diabetes. The diagnosis is based on WHO classification, which is a clinical classification and misses the autoimmune diabetes in adults. Therefore, among the clinically diagnosed NIDDM cases, there can be a certain number of patients with latent autoimmune diabetes in adults (LADA). The MICA gene is located in the MHC class I region and is expressed by monocytes, keratinocytes, and endothelial cells. Sequence determination of the MICA gene identifies trinucleotide repeat (GCT) microsatellite polymorphism, which identifies 5 alleles with 4, 5, 6, and 9 repetitions of GCT (A4, A5, A6, and A9) or 5 repetitions of GCT with 1 additional G insertion for al…

AdultMaleGeneral Biochemistry Genetics and Molecular Biologylaw.inventionHistory and Philosophy of ScienceGene FrequencylawDiabetes mellitusMHC class ImedicineHumansGenetic Predisposition to DiseaseAlleleAge of OnsetPolymerase chain reactionAllelesbiologyGeneral NeuroscienceHistocompatibility Antigens Class Imedicine.diseaseLatviastomatognathic diseasesDiabetes Mellitus Type 2HaplotypesImmunologybiology.proteinMicrosatelliteFemaleAge of onsetAntibodyTrinucleotide repeat expansionMicrosatellite RepeatsAnnals of the New York Academy of Sciences
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