0000000000852074
AUTHOR
Sudipta Kalita
To be or not to be heavier: The role of dermal bones in the buoyancy of the Late Triassic temnospondyl amphibian Metoposaurus krasiejowensis.
Stereospondyli are a clade of large aquatic temnospondyls known to have evolved a large dermal pectoral girdle. Among the Stereospondyli, metoposaurids in particular possess large interclavicles and clavicles relative to the rest of the postcranial skel-eton. Because of the large size of these dermal bones, it was first proposed that they served as ballast during hydrostatic buoyancy control which assisted metoposaurids to live a bottom-dwelling mode of life. However, a large bone need not necessarily be heavy, for which determining the bone compactness becomes crucial for under-standing any such adaptation in these dermal bones. Previous studies on the evolu-tion of bone adaptations to aqu…
An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Abstract Background Neoplasms are common across the animal kingdom and seem to be a feature plesiomorphic for metazoans, related with an increase in somatic complexity. The fossil record of cancer complements our knowledge of the origin of neoplasms and vulnerability of various vertebrate taxa. Here, we document the first undoubted record of primary malignant bone tumour in a Mesozoic non-amniote. The diagnosed osteosarcoma developed in the vertebral intercentrum of a temnospondyl amphibian, Metoposaurus krasiejowensis from the Krasiejów locality, southern Poland. Results A wide array of data collected from gross anatomy, histology, and microstructure of the affected intercentrum reveals th…
Additional file 7 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 7. Close-ups of osteocytes lacunae in the neoplasm-affected part of vertebral intercentrum showing their subspherical shapes.
Additional file 6 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 6. Photoscan of ground section of normal, non-altered anterodorsal vertebral intercentrum of Metoposaurus krasiejowensis, for comparative purposes, specimen number UOPB 00118 [1].
Additional file 1 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 1. 3D model of ZPAL Ab III/2467.
Additional file 3 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 3. 3D model of pathologically-altered intercentrum, virtually extracted from microtomographic scans.
Additional file 4 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 4. 3D model of bone outgrowth, virtually extracted from microtomographic scans.
Additional file 5 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 5. 3D model of ZPAL Ab III/2467 with marked scanning planes.
Additional file 2 of An insight into cancer palaeobiology: does the Mesozoic neoplasm support tissue organization field theory of tumorigenesis?
Additional file 2. Juxtaposition of the 3D model of ZPAL Ab III/2467 and 3D volumetric reconstructions of the remaining normal part of the pathologically-altered intercentrum and bone outgrowth (tumour).