0000000000867230

AUTHOR

Conti G

showing 2 related works from this author

Agalsidase alpha and hearing in Fabry disease: data from the Fabry Outcome Survey.

2006

Fabry disease is an X-linked lysosomal storage disorder characterized by multi-organ dysfunction, including hearing loss - mainly sensorineural. The recent introduction of enzyme replacement therapy (ERT) has resulted in improvements in renal and cardiac function, pain and quality of life. One study has also suggested small improvements in high-frequency hearing. In this paper, we study the effect of ERT on hearing in patients in the Europe-wide database - the Fabry Outcome Survey (FOS). Twenty-six patients in FOS had pure-tone audiometry performed up to 6 months before starting ERT with agalsidase alpha and after a median of 12 months of treatment. We assessed changes in hearing thresholds…

Cardiac function curveAdultMalemedicine.medical_specialtyHearing lossClinical BiochemistryAlpha (ethology)AudiologyBiochemistryQuality of lifeotorhinolaryngologic diseasesmedicineHumansLongitudinal Studiesmedicine.diagnostic_testbusiness.industryVascular diseaseGeneral MedicineEnzyme replacement therapymedicine.diseaseFabry diseaseSurgeryIsoenzymesTreatment OutcomeSensory Thresholdsalpha-GalactosidaseAudiometry Pure-ToneFabry DiseaseFemalemedicine.symptomAudiometrybusinessEuropean journal of clinical investigation
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Surgical Antimicrobial Prophylaxis in Pediatric Patients Undergoing Plastic Surgery: A RAND/UCLA Appropriateness Method Consensus Study

2022

For many years, it was clearly shown that surgical procedures might be associated with surgical site infection (SSI). Many scientific institutions prepared guidelines to use in surgery to reduce abuse and misuse of antibiotics. However, in the general guidelines for surgical antibiotic prophylaxis, plastic surgical procedures are not addressed or are only marginally discussed, and children were almost systematically excluded. The main aim of this Consensus document is to provide clinicians with recommendations on antimicrobial prophylaxis for pediatric patients undergoing plastic surgery. The following scenarios were considered: clean plastic surgery in elective procedures with an exclusive…

Microbiology (medical)Settore MED/38 - Pediatria Generale e SpecialisticawoundBiochemistryMicrobiologyantibiotics; burn; pediatric infectious diseases; plastic surgery; surgical antibiotic prophylaxis; woundantibioticspediatric infectious diseaseInfectious Diseasessurgical antibiotic prophylaxisantibioticplastic surgeryburnPharmacology (medical)surgical antibiotic prophylaxiGeneral Pharmacology Toxicology and PharmaceuticsKeywords: antibioticpediatric infectious diseaseswound.
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