0000000000872679
AUTHOR
G. Gambardella
showing 2 related works from this author
Alaisa-Halaesa. Scavi e ricerche (1970-2007)
2009
Experimental investigations on a model of cryogenic edema.
1987
The role of mechanisms underlying formation and progression of vasogenic brain edema is investigated. On this purpose, cerebral edema was produced by cortical freezing in two different brain situations in rabbits (with or without replacement of bone flap). BBB (Blood-Brain Barrier) breakdown was evaluated by observation of Evans blue extravation, while a histopathological evaluation was carried out by light and transmission electron microscopy. Water content of brain tissue was determined by the wet/dry weight ratio method. Comparison of extension and intensity of cerebral edema between these two groups of animals shows a statistically significant difference: there was evidence of higher wa…