0000000000874428

AUTHOR

Robert H. Young

showing 2 related works from this author

Ovarian Endometrioid-like Yolk Sac Tumor Treated by Surgery Alone, with Recurrence at 12 Years

1999

Abstract We describe the case of a stage Ia endometrioid-like yolk sac tumor (YST) of the ovary, which was originally misdiagnosed as a malignant struma ovarii and not treated with adjuvant chemotherapy. After 12 years, a contralateral dermoid cyst was excised along with a small omental nodule of partially necrotic and calcified endometrioid-like YST. No tumor was detected in several other biopsy specimens, and a peritoneal lavage was negative for tumor cells. Since there was no evidence of remaining tumor and the serum α-fetoprotein (AFP) level was normal after the second operation, the patient was followed. Serial serum AFP levels remained normal for 4 months. At a second-look laparotomy …

AdultReoperationPathologymedicine.medical_specialtyTime Factorsmedicine.medical_treatmentOvaryLaparotomyBiopsyHumansMedicineYolk sacPeritoneal NeoplasmsOvarian Neoplasmsmedicine.diagnostic_testbusiness.industryEndodermal Sinus TumorObstetrics and GynecologyMalignant Struma Ovariimedicine.diseaseSurgerymedicine.anatomical_structureOncologyDermoid cystFemaleHistopathologyNeoplasm Recurrence LocalPouchbusinessOmentumGynecologic Oncology
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Inhibin-α, CD99, HEA125, PLAP, and chromogranin immunoreactivity in testicular neoplasms and the androgen insensitivity syndrome

2000

We investigated 115 testicular and 3 epididymal tumors and 6 cases of the complete androgen insensitivity syndrome (AIS) for the expression of inhibin-alpha, CD99, HEA125, PLAP, and chromogranin, using monoclonal antibodies and standard immunhistochemical techniques. Ihibin-alpha was detected in the neoplastic cells in 27 of 27 primary Leydig cell tumors (LCTs), 1 of 1 metastatic LCT, 6 of 20 Sertoli cell tumors (SCTs), 4 of 5 juvenile granulosa cell tumors (GCTs), and 2 of 5 unclassified sex cord-stromal tumors (USCSTs). Except for 2 choriocarcinomas, the choriocarcinomatous component of 1 mixed germ cell tumor, and a small focus of inhibin-positive syncytiotrophoblast in 1 embryonal carci…

Maleendocrine systemmedicine.medical_specialtyPathologyendocrine system diseasesCD9912E7 AntigenBiologyPathology and Forensic MedicineEmbryonal carcinomaTesticular NeoplasmsAntigens CDAntigens NeoplasmRete testisInternal medicineBiomarkers TumorChromograninsmedicineHumansInhibinsRhabdomyosarcomaGranulosa Cell TumorEpididymisLeydig cellProteinsChromogranin AAndrogen-Insensitivity Syndromemedicine.diseaseSertoli cellNeoplasm Proteinsmedicine.anatomical_structureEndocrinologyFluorescent Antibody Technique DirectAntigens Surfacebiology.proteinGerm cell tumorsPeptidesCell Adhesion MoleculesHuman Pathology
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