0000000000880742
AUTHOR
Amy Davis
A step towards a field based agility test in team sports. A perspective on return to play criteria
Introduction: Agility performance tests can be limited by the requirement for force plates, timing gates and expensive camera systems (Correia et al., 2012; Green, Blake, & Caulfield, 2011) making application into rehabilitation programs practically challenging. The aims of this study were to assess the reliability of a field based 1v1 agility test encompassing perceptualaction performance that could be replicated in applied settings. A secondary aim was to assess the relationship between the 1v1 agility test with a range of physical performance tests including the commonly used Y step test (Paul, Gabbett, & Nassis, 2016). Methods: Twenty-eight male rugby union players volunteered (Mean ± S…
X Chromosome Contribution to the Genetic Architecture of Primary Biliary Cholangitis
Background & aims: Genome-wide association studies in primary biliary cholangitis (PBC) have failed to find X chromosome (chrX) variants associated with the disease. Here, we specifically explore the chrX contribution to PBC, a sexually dimorphic complex autoimmune disease. Methods: We performed a chrX-wide association study, including genotype data from 5 genome-wide association studies (from Italy, United Kingdom, Canada, China, and Japan; 5244 case patients and 11,875 control individuals). Results: Single-marker association analyses found approximately 100 loci displaying P < 5 × 10-4, with the most significant being a signal within the OTUD5 gene (rs3027490; P = 4.80 × 10-6; odds…