Author: Niklas Julian Lentelink

0000000000886981

AUTHOR

Niklas Julian Lentelink

0000-0002-6197-8374

Synthesis of trifluoromethyl-substituted 1,2,6-thiadiazine 1-oxides from sulfonimidamides under mechanochemical conditions

TBS-protected or NH-sulfonimidamides react with β-alkoxyvinyl trifluoromethylketones under solvent-free mechanochemical conditions to give 3-trifluoromethyl-substituted three-dimensional 1,2,6-thiadiazine 1-oxides. C4-Functionalized products can be obtained by starting from cyclic enones and brominations of the initially formed heterocycles. The stability of the products was investigated by varying the pH value and storage under aerobic conditions.

research product

CCDC 2109381: Experimental Crystal Structure Determination

Related Article: Marco Thomas Passia, Jan-Hendrik Sch��bel, Niklas Julian Lentelink, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2021|Org.Biomol.Chem.|19|9470|doi:10.1039/D1OB01912K

research product

CCDC 2109331: Experimental Crystal Structure Determination

Related Article: Marco Thomas Passia, Jan-Hendrik Sch��bel, Niklas Julian Lentelink, Khai-Nghi Truong, Kari Rissanen, Carsten Bolm|2021|Org.Biomol.Chem.|19|9470|doi:10.1039/D1OB01912K

research product

PEPhysical Sciences and Engineering
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LSLife Sciences
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