Atherosclerosis in females patients with rheumatoid arthritis; a two years follow-up.

Atherosclerosis in female patients with rheumatoid arthritis: a two years of follow up

pentoxifylline inhibits vgamma9/vdelta2 t lymphocyte activation of patients with active behçet's disease

The aim ofthis study is to evaluate the in vitro effect ofpentoxifylline (PTX) on T Vy9No21ymphocyte function in Beheet's disease (DO). We investigated the effect of PTX on Vy9No2 T cell expansion and expression of TNFRII receptor and perforin content before and after PTX addition by means of FACS analysis lymphocyte cultures from patients with active and inactive DO and healthy subjects. The addition of PTX at a concentration of 1 mg/ml determined a significant inhibition of cell expansion, a down regulation of TNF receptor expression and inhibited the PMA-induced degranulation of perforin. Taken together these data indicate that PTX is capable of interfering with Vy9No2 T cell function in…

The level of solubile granzyme A is elevated in the plasma and in the Vγ9/Vδ2 T cell culture supernatants of patients with active Behçet's disease.

Atherosclerosis in female patients with rheumatoid arthritis; a two years follow-up