0000000000889159

AUTHOR

Paolo Meneguzzo

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Catechol-O-Methyltransferase (COMT) Val158Met Polymorphism and Eating Disorders: Data From a New Biobank and Meta-Analysis of Previously Published St…

2017

Objectives: We investigated whether catechol-O-methyltransferase (COMT) Val158Met polymorphism is associated with eating disorders (EDs). Methods: We conducted a systematic literature search of studies published until 15 January 2017 and added data from the Italian ‘Biobanca Veneta per i Disturbi Alimentari’ biobank, performing a meta-analysis comparing COMT Val158Met genotype and allele frequencies in EDs and anorexia nervosa (AN) or bulimia nervosa (BN) patients versus controls. Results: Ten studies plus Biobanca Veneta per i Disturbi Alimentari (ED: n = 920, controls: n = 261 controls) with 3541 ED patients (AN = 2388; BN = 233) and 3684 controls were included. There were no significant …

Anorexia NervosaGenotypeVal158MetCatechol O-MethyltransferasePolymorphism Single Nucleotidecatechol-O-methyltransferase (COMT)polymorphismFeeding and Eating DisordersGene FrequencyCase-Control Studiesmental disordersJournal ArticleHumansBulimia NervosaVal158Met; anorexia nervosa; bulimia nervosa; catechol-O-methyltransferase (COMT); polymorphismBiological Specimen BanksEuropean eating disorders review : the journal of the Eating Disorders Association
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