0000000000890247

AUTHOR

Graziella Caselli

showing 2 related works from this author

Immunogenetics, Gender, and Longevity

2007

In this article we discuss relevant data on aging, longevity, and gender with particular focus on inflammation gene polymorphisms which could affect an individual's chance to reach the extreme limit of human life. The present review is not an extensive revision of the literature, but rather an expert opinion based on selected data from the authors' laboratories. In 2000-2005 in the more developed regions, the life expectancy at birth is 71.9 years for men (78.3 in Japan) and 79.3 years for women (86.3 in Japan). Indeed, gender accounts for important differences in the prevalence of a variety of age-related diseases. Considering people of far-advanced age, demographic data document a clear-c…

MaleGerontologyAgingmedia_common.quotation_subjectLongevityPopulationDiseaseGeneral Biochemistry Genetics and Molecular BiologyHistory and Philosophy of ScienceHLA AntigensImmunogeneticsHumansMedicineSex Ratioeducationmedia_commonInflammationeducation.field_of_studySuccessful agingbusiness.industryGeneral NeuroscienceMortality rateAging Immune response Inflammation LongevityLongevityInfectious disease (medical specialty)Life expectancyFemalebusinessDeveloped countryAnnals of the New York Academy of Sciences
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Pathophysiology of ageing, longevity and age related diseases

2007

Abstract On April 18, 2007 an international meeting on Pathophysiology of Ageing, Longevity and Age-Related Diseases was held in Palermo, Italy. Several interesting topics on Cancer, Immunosenescence, Age-related inflammatory diseases and longevity were discussed. In this report we summarize the most important issues. However, ageing must be considered an unavoidable end point of the life history of each individual, nevertheless the increasing knowledge on ageing mechanisms, allows envisaging many different strategies to cope with, and delay it. So, a better understanding of pathophysiology of ageing and age-related disease is essential for giving everybody a reasonable chance for living a …

lcsh:Immunologic diseases. AllergyGerontologyAgingmedia_common.quotation_subjectImmunologyReviewDiseaselcsh:Geriatricslongevity in Sicily and Sardiniaddc:570Age relatedMedicinecancerLife historymedia_commonimmunosenescenceEnd pointGeriatrics gerontologybusiness.industryLongevityImmunosenescencelcsh:RC952-954.6AgeingageingAging T-Lymphocytes aged micelcsh:RC581-607business
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