0000000000890697

AUTHOR

Steffen D. Kriechbaum

showing 2 related works from this author

Non-Invasive Approach for Evaluation of Pulmonary Hypertension Using Extracellular Vesicle-Associated Small Non-Coding RNA.

2019

Extracellular vesicles are released by numerous cell types of the human body under physiological but also under pathophysiological conditions. They are important for cell&ndash

0301 basic medicineMalemedicine.drug_classHypertension Pulmonarylcsh:QR1-502Piwi-interacting RNA030204 cardiovascular system & hematologyBiologyBiochemistrylcsh:MicrobiologyArticlechronic thromboembolic pulmonary hypertension03 medical and health sciencesExtracellular Vesicles0302 clinical medicinemicroRNAmedicineNatriuretic peptideHumansMolecular BiologyAgedsmall non-coding RNApulmonary diseaseExtracellular vesicleMiddle Agedmedicine.diseaseNon-coding RNAPulmonary hypertensionCell biology030104 developmental biologymedicine.anatomical_structureCase-Control StudiesVascular resistanceBiomarker (medicine)RNA Small UntranslatedbiomarkerFemaleextracellular vesiclesright heart dysfunctionBiomolecules
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Mid-regional pro-atrial natriuretic peptide and copeptin as indicators of disease severity and therapy response in CTEPH

2020

Background Chronic thromboembolic pulmonary hypertension (CTEPH) leads to right heart failure. Pulmonary endarterectomy (PEA) or balloon pulmonary angioplasty (BPA) restore pulmonary haemodynamics and allow cardiac recovery. This study examined the relationship of copeptin and mid-regional pro-atrial natriuretic peptide (MR-proANP) levels to disease severity and therapy response. Methods This observational cohort study included 125 patients (55 PEA/70 BPA) who underwent treatment and completed a 6-/12-month follow-up. Biomarkers, measured at baseline, prior to every BPA and at follow-up, were compared to 1) severe disease at baseline (right atrial pressure (RAP) ≥8 mmHg and cardiac index ≤2…

Pulmonary and Respiratory MedicinePulmonary Vascular Disease7medicine.medical_specialtybusiness.industrymedicine.drug_classmedicine.medical_treatmentlcsh:RArea under the curveCentral venous pressureCardiac indexlcsh:MedicineOriginal Articlesmedicine.anatomical_structureCopeptinInternal medicineAngioplastyVascular resistancemedicineCardiologyNatriuretic peptidebusinessCohort studyERJ Open Research
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