0000000000900273
AUTHOR
A. Petit
Les maladies du bois de la vigne : recherches pour apporter des solutions de lutte aux Professionnels
Les travaux réalisés sur deux maladies du bois de la vigne (esca, BDA) ont montré leur effet sur la récolte et la croissance de la pousse printanière qui était annulé deux années après l’apparition des symptômes. Ces maladies ont aussi conduit à des modifications des propriétés analytiques des moûts et des vins. Les vins issus de raisins collectés sur des ceps symptomatiques n’étaient pas toujours les plus dépréciés. Les études effectuées sur le cycle biologique ont permis de mettre au point des outils pour différencier les individus de deux espèces de Botryosphaeriaceae et des outils d’hybridation in situ qui permettront de les localiser précisément dans les tissus. Elles ont aussi identif…
The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study
Abstract Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries.…
Wiedemann-Steiner syndrome as a major cause of syndromic intellectual disability: A study of 33 French cases.
International audience; Wiedemann-Steiner syndrome (WSS) is a rare syndromic condition in which intellectual disability (ID) is associated with hypertrichosis cubiti, short stature, and characteristic facies. Following the identification of the causative gene (KMT2A) in 2012, only 31 cases of WSS have been described precisely in the literature. We report on 33 French individuals with a KMT2A mutation confirmed by targeted gene sequencing, high-throughput sequencing or exome sequencing. Patients' molecular and clinical features were recorded and compared with the literature data. On the molecular level, we found 29 novel mutations. We observed autosomal dominant transmission of WSS in 3 fami…