0000000000904586

AUTHOR

G Müller

showing 4 related works from this author

Erythropoietin for the treatment of anemia of malignancy associated with neoplastic bone marrow infiltration.

1990

This clinical trial was performed to study the effects of intravenously (IV) administered recombinant human (rh) erythropoietin (EPO) at escalating doses (150, 300, and 450 U/kg, administered as an IV bolus injection, twice weekly, for 6, 4, and 4 weeks, respectively) in five patients with low-grade non-Hodgkin's lymphoma (Ig NHL) and bone marrow involvement and one patient with multiple myeloma (MM). All patients were anemic due to underlying disease. None of the patients had a history of bleeding, hemolysis, renal insufficiency, or other disorders causing anemia in addition to bone marrow infiltrating malignancy. Endogenous EPO serum levels were significantly increased in all patients (7…

MaleCancer Researchmedicine.medical_specialtyAnemiaHematocritMalignancyGastroenterologyBone Marrowhemic and lymphatic diseasesInternal medicineNeoplasmsMedicineHumansErythropoiesisBlood CoagulationErythropoietinMultiple myelomaAgedClinical Trials as Topicmedicine.diagnostic_testbusiness.industryTumor Necrosis Factor-alphaAnemiaMiddle Agedmedicine.diseaseLymphomaHematopoiesisKineticsmedicine.anatomical_structureOncologyErythropoietinImmunologyFerritinsErythropoiesisFemaleBone marrowbusinessmedicine.drugJournal of clinical oncology : official journal of the American Society of Clinical Oncology
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Erratum: The lateral trigger probability function for the ultra-high energy cosmic ray showers detected by the Pierre Auger Observatory (Astroparticl…

2012

The Fig. 7, originally consisting of 4 panels, was truncated in the printed version (the last panel was missing). The complete version is printed again

Astronomy and Astrophysics
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Defining the role of common variation in the genomic and biological architecture of adult human height

2014

Item does not contain fulltext Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated approximately 2,000, approximately 3,700 and approximately 9,500 SNPs explained approximately 21%, approximately 24% and approximately 29% of phenotypic variance. Furthermore, all common variants together captured 60% of heritability. The 697 variants clustered in 423 loci were enriched for genes, pathways and tissue types known to be involved in growth and together implicated genes…

Netherlands Twin Register (NTR)BIO/12 - BIOCHIMICA CLINICA E BIOLOGIA MOLECOLARE CLINICAElectronic Medical Records and Genomics (eMEMERGEGE) ConsortiumMedizinGenome-wide association studyAdult; Analysis of Variance; Body Height/genetics; European Continental Ancestry Group/genetics; Genetic Variation/genetics; Genetics Population; Genome-Wide Association Study/methods; Humans; Oligonucleotide Array Sequence Analysis; Polymorphism Single Nucleotide/geneticsheritability0302 clinical medicineGenome-wideEuropean Continental Ancestry Group/geneticsSNPSOligonucleotide Array Sequence AnalysissnpsGenetics & Heredityddc:616GeneticsMedical And Health Sciences0303 health scienceseducation.field_of_studyvariantsBody Height/geneticsGENETIC-VARIATIONBiological SciencesPolymorphism Single Nucleotide/geneticsGenetic Variation/geneticsUrological cancers Radboud Institute for Health Sciences [Radboudumc 15]Genome-Wide Association Study/methodsbody heightgenetic-variationLife Sciences & BiomedicineSingle Nucleotide/geneticsHumanAdultEuropean Continental Ancestry GroupPopulationPopulationSingle-nucleotide polymorphismBiologyPolymorphism Single NucleotideArticleWhite PeopleNOcomplex traits03 medical and health sciencesGenetic variationheritability adult height/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_GeneticsHumansPolymorphismHuman heightPAGEGE ConsortiumeducationGeneVLAG030304 developmental biologyGlobal NutritionWereldvoedingAnalysis of VarianceGenome-wide; heritability; variantsgenome-wide association studyScience & TechnologyWhitesOligonucleotide Array Sequence AnalysiMUTATIONSCOMPLEX TRAITSta1184Klinisk medicinpopulation geneticsGenetic VariationHeritabilityta3121mutationsGenetic architectureBody HeightGenetics Populationgenetic variationMIGen ConsortiumInflammatory diseases Radboud Institute for Health Sciences [Radboudumc 5]Clinical Medicine030217 neurology & neurosurgeryheightLifeLines Cohort StudyDevelopmental BiologyGenome-Wide Association StudyNature genetics
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Results of a self-triggered prototype system for radio-detection of extensive air showers at the Pierre Auger Observatory

2012

We describe the experimental setup and the results of RAuger, a small radio-antenna array, consisting of three fully autonomous and self-triggered radio-detection stations, installed close to the center of the Surface Detector (SD) of the Pierre Auger Observatory in Argentina. The setup has been designed for the detection of the electric field strength of air showers initiated by ultra-high energy cosmic rays, without using an auxiliary trigger from another detection system. Installed in December 2006, RAuger was terminated in May 2010 after 65 registered coincidences with the SD. The sky map in local angular coordinates (i.e., zenith and azimuth angles) of these events reveals a strong azi…

[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]self-triggergeomagnetic effect.media_common.quotation_subjectAstrophysics::High Energy Astrophysical PhenomenaFOS: Physical sciencesCosmic ray01 natural sciencesElectric field0103 physical sciencesextensive air showers010306 general physicsCosmic raysInstrumentationMathematical PhysicsZenithmedia_commonPhysicsPierre Auger ObservatoryHigh Energy Astrophysical Phenomena (astro-ph.HE)010308 nuclear & particles physicsLarge detector systems for particle and astroparticle physics[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE]DetectorAstrophysics::Instrumentation and Methods for AstrophysicsCosmic rayextensive air showerAntennas; Large detector systems for particle and astroparticle physics3. Good healthComputational physicsAzimuthEarth's magnetic fieldSkyAntennasAstrophysics - High Energy Astrophysical Phenomenaradio-detection
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