0000000000905034

AUTHOR

Hans G. Börner

Modular approach toward bioactive fiber meshes carrying oligosaccharides

A modular strategy toward (bio)functional nanofiber meshes by electrospinning is described. In contrast to commonly established, multistep protocols or complex spinning setups, a straightforward single-step procedure is investigated to obtain polymer nanofibers with pentafluorophenyl (Pfp)-activated esters on the surface. The aim was to electrospin, for the first time, poly(pentafluorophenyl methacrylate) (PPfpMA) and PPfpMA/poly(epsilon-caprolactone) (PCL) blends, resulting in reactive nanofibers with fiber surfaces that can be functionalized with suitable bioactive entities. While PPfpMA fibers are brittle the spinning of PCL/PPfpMA blends leads to improved mechanical stability of the obt…

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Reply to Comment on Measurement of quantum states of neutrons in the Earth's gravitational field

Physical review / D 68(10), 108702 (2003). doi:10.1103/PhysRevD.68.108702

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Measurement of quantum states of neutrons in the Earth's gravitational field

The lowest stationary quantum state of neutrons in the Earth's gravitational field is identified in the measurement of neutron transmission between a horizontal mirror on the bottom and an absorber/scatterer on top. Such an assembly is not transparent for neutrons if the absorber height is smaller than the ``height'' of the lowest quantum state.

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Topology-Dependent Swichability of Peptide Secondary Structures in Bioconjugates with Complex Architectures

Peptide sequences, which exhibit a reversible pH-responsive coil to α-helix secondary structure transition, are conjugated to polymer precursors to yield linear AB and graft ABA peptide-poly(ethylene oxide) conjugates. While the PEO B-block is comparable, the conjugates differ in topologies of the peptide bearing A-blocks. The influences of topology on the structure transitions in the peptide segments are investigated, comparing linear AB-bioconjugates with graft ABA-bioconjugates having multiple peptide segments combined in star or pom-pom topologies.

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