0000000000906126

AUTHOR

A. Benani

showing 9 related works from this author

Redox state alteration modulates astrocyte glucuronidation.

2004

We have investigated the effects of mild oxidative conditions on drug-metabolizing enzyme activity in rat cultured astrocytes. These experimental conditions promoting an oxidative environment were obtained by short exposure to a low concentration of menadione (5 microM) for a short duration (15 min). This resulted in the rapid and transient production of reactive oxygen species (+130%), associated with a decrease in GSH cellular content (-24%), and an increase in total protein oxidation (+26%), but promoted neither PGE(2) nor NO production. This treatment induced a rapid and persistent decrease in astrocyte glucuronidation activities, which was totally prevented by N-acetyl-l-cysteine. Thes…

MaleCell SurvivalGlucuronidationApoptosisGlucuronatesOxidative phosphorylationmedicine.disease_causeProtein oxidationBiochemistryRedoxchemistry.chemical_compoundMenadionePhysiology (medical)CricetinaemedicineAnimalsProtein IsoformsRNA MessengerGlucuronosyltransferaseRats WistarPromoter Regions GeneticCells Culturedchemistry.chemical_classificationInflammationReactive oxygen speciesBase SequenceVitamin K 3GlutathioneHydrogen PeroxideMolecular biologyGlutathioneCell biologyRatschemistryAstrocytesFemaleReactive Oxygen SpeciesOxidation-ReductionOxidative stressFree radical biologymedicine
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MOESM5 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 5. List of the 2 and 8 KEGG pathways significantly enriched in the over- and under-expressed genes in the blood.

funginatural sciences
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MOESM3 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 3. List of the differentially expressed genes (LE vs. CT) in each tissue.

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MOESM8 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 8. Composition of the diets.

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MOESM4 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 4. List of the 26 and 44 KEGG pathways significantly enriched in the over- and under-expressed genes in the hypothalamus.

funginatural sciences
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MOESM7 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 7. List of the KEGG pathways significantly associated with WGCNA’s modules detected using blood DEG.

genetic structuresfunginatural sciencessense organs
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MOESM1 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 1. Means (±SD) and significance for Body weight at 17 weeks for the effect of the diet, the line and their interaction.

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MOESM6 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 6. List of the KEGG pathways significantly associated with WGCNA’s modules detected using hypothalamic DEG.

genetic structuresfunginatural sciencessense organs
researchProduct

MOESM2 of Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue tran…

2019

Additional file 2. List of the genes uniquely expressed in each tissue.

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