Author: S Minafra

0000000000907861

AUTHOR

S Minafra

showing 4 related works from this author

Proteomic analysis of Herceptin-resistance breast cancer cells

2009

researchProduct

Comparative proteomics of breast cancer surgical tissues

2009

proteomics bioinformatics

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Herceptin-resistance in breast cancer cells: a proteomic study.

2009

HER-2 is a cell membrane protein that belongs to the ErbB family of receptor tyrosine kinases (HER-1, HER-2, HER-3, HER-4). The over-expression of HER-2, which results in the 25-30% of breast cancer patients, is considered a predictive and prognostic marker for breast cancer malignancy and invasiveness and makes HER-2 an excellent therapeutic target. In the last years new therapeutic strategies have been improved in order to better deal tumor diseases an to minimize collateral effects due to classic chemotherapy in patients. In this way, a new approach was the somministration of humanized antibodies directed against tumor-associated molecular targets. Among these ones Herceptin, an anti-neo…

Herceptin breast cancer proteomicsSettore BIO/06 - Anatomia Comparata E Citologia

researchProduct

Herceptin-resistance in breast cancer cells: a proteomic approach

2009

Breast cancer Herceptin

researchProduct

PEPhysical Sciences and Engineering
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LSLife Sciences
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