0000000000910666

AUTHOR

D. Benahmed

showing 2 related works from this author

Eosinophil-selective mediators in human strongyloidiasis

2006

SUMMARY Strongyloides stercoralis infection is characterized by the production of IgE and eosinophils in peripheral blood. Experimental studies have demonstrated that eosinophils play an important role in protection against Strongyloides stercoralis, but the mechanisms regulating eosinophils are not known. In this study we have focused on analysing the molecules that selectively regulate eosinophil migration, namely eotaxin and interleukin-5 (IL-5), using an enzyme-linked immunosorbent assay in patients with strongyloidiasis. Serum expression of eotaxin and IL-5 were significantly increased in patients compared with the control group. This rise suggests that selective mediators of the eosin…

AdultChemokine CCL11MaleEotaxinAdolescentImmunologyAntibodies HelminthImmunoglobulin EStrongyloides stercoralisEosinophil migrationmedicineAnimalsHumansInterleukin 5AgedEosinophil cationic proteinbiologyImmunoglobulin EMiddle Agedrespiratory systemEosinophilmedicine.diseasebiology.organism_classificationEosinophilsChemotaxis LeukocyteStrongyloidiasismedicine.anatomical_structureChemokines CCImmunologyStrongyloidiasisbiology.proteinFemaleParasitologyInterleukin-5Strongyloides stercoralisParasite Immunology
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Biological characterization of glutaraldehyde-modified Parietaria judaica pollen extracts.

2004

Summary Background Allergoids are widely used in specific immunotherapy (SIT) for the treatment of IgE-mediated allergic diseases, but all techniques for standardization of conventional allergic extracts may not be appropriate for standardization of a glutaraldehyde (GA)-modified extract because of the unique characteristics of these extracts. Objective To assess an accurate methodology for standardization of chemically modified extracts. Methods GA-modified extracts from Parietaria judaica pollen were purified by diafiltration. Biochemical properties were investigated by determination of amino groups, chromatography, and SDS-PAGE. The IgE-binding activity was determined by skin prick test,…

AdultMaleAdolescentImmunologyLymphocyte proliferationBasophilImmunologic Testsmedicine.disease_causechemistry.chemical_compoundAllergenmedicineHypersensitivityImmunology and AllergyAnimalsHumansSkin TestsbiologyChemistryPlant ExtractsAllergensMiddle Agedbiology.organism_classificationDiafiltrationAllergoidBasophil activationmedicine.anatomical_structureParietariaBiochemistryDesensitization ImmunologicGlutaralImmunologyParietaria judaicaPollenFemaleGlutaraldehydeRabbitsFiltrationClinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
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