Valutazione della risposta al trattamento con termoablazione percutanea con radiofrequenza dell’epatocarcinoma: ruolo dell’ecografia con mezzo di contrasto

The attenuation of bronchodilatory effect of deep inspiration (DI) in COPD is related to reduced airway distensibility as measured by HRCT.

Densitometria TC nella diagnosi radiologica differenziale tra polmone senile ed enfisema nell’ anziano

The Bronchodilatory Ability of Deep Inspiration (DI) Is Impaired in Scleroderma

Distribution and lower limit of normal of computed tomography (CT) density in non emphysematous senile lungs

CT densitometry-based differential diagnosis between emphysematous and non-emphysematous lungs in elderly patients.

Purpose Methods and Materials Results Conclusion References Personal Information

Early Lung Function Abnormalities in Acromegaly.

BACKGROUND: Acromegaly is an insidious disorder caused by a pituitary growth hormone (GH)-secreting adenoma resulting in high circulating levels of GH and insulin-like growth factor I (IGF-I). Respiratory disorders are common complications in acromegaly, and can severely impact on quality of life, eventually affecting mortality. OBJECTIVES: The present study aimed to explore structural and functional lung alterations of acromegalic subjects. METHODS: We enrolled 10 consecutive patients (M/F: 5/5) affected by acromegaly. In all patients, magnetic resonance imaging (MRI) revealed the presence of pituitary tumor. All patients underwent clinical, lung functional, biological, and radiological as…

Ruolo dell' HRCT nello studio del rimodellamento delle pareti delle vie aeree nell' asma.

Correlazioni tra rilievi HRCT e test funzionali nella interstiziopatia polmonare sclerodermica

Non-invasive diagnosis in a case of bronchopulmonary sequestration and proposal of diagnostic algorhythm

The case of a 43-year-old woman with intralobar pulmonary sequestration, Pryce type one, is presented. The medical history was characterised by recurrent bronchopneumonia, productive cough with purulent sputum and hemoptysis in the last three years. Diagnosis was made by CT angiography: multiplanar, maximum intensity projection and volume rendering reconstructions were visualised. A volume reduction of middle and lower lobe with multiple cyst-like bronchiectasis was detected and no evident relationship with tracheobronchial tree was pointed out. Reconstructions aimed at evaluating bronchial structures demonstrated no patency of middle and lower lobar bronchi. The study carried out after con…

Valutazione della risposta bronchiale ai respiri profondi mediante HRCT nell’asma e nella BPCO

HRCT evaluation of bronchial response to deep inspiration in asthma and chronic obstructive pulmonary disease (COPD)

Purpose Methods and Materials Results Conclusion References Personal Information

Digital cineradiographic study of swallowing in infants with neurologic disease. Our experience

Airway wall thickness by HRCT in patients with COPD.

Virtual bronchoscopy in patients with central endobronchial stenosing lesions. Technique optimisation with single slice spiral CT.

PURPOSE: To describe an original protocol for single slice spiral Computed Tomography (CT) virtual bronchoscopy in the evaluation of patients with central airway stenoses and compare the results with fibreoptic bronchoscopy. MATERIALS AND METHODS: Ten patients (4 female and 6 male; age range 22-60 years; mean age 44 years) with endobronchial disease diagnosed by fibreoptic bronchoscopy (8 malignant tumours, 1 benign tumour and 1 fibroid stenosis) underwent virtual bronchoscopy with single slice spiral CT. A panoramic spiral CT scan of the whole chest was first obtained. Once the area of interest had been identified, a new contrast enhanced scan was performed, from bottom to top, with the fo…

Alterations of the beneficial effect of deep inspiration in scleroderma: relationships between lung function and imaging.

<i>Background:</i> It has been postulated that the beneficial effects of deep inspiration are dependent on the magnitude of airway distension by virtue of airway to parenchyma interdependence. <i>Objective:</i> This study was designed to examine whether the changes that occur in pulmonary fibrosis affect the beneficial effect of deep inspiration. <i>Methods:</i> Thirty-one subjects with scleroderma underwent lung volume and diffusion capacity assessment as well as high-resolution computed tomography. To assess the effect of deep inspiration, each subject underwent methacholine provocations in the absence of deep breaths. When the targeted change in lung f…

Il polmone nell' età senile

Validation of lung densitometry threshold at CT for the distinction between senile lung and emphysema in elderly subjects

Background and Aims. An ageing lung is characterised by distal airspace enlargement without alveolar wall destruction: therefore the anatomical distinction between senile lung and emphysema is clear-cut. In clinical settings the definition of precise boundaries between normalcy and pathology is more difficult with the risk of overdiagnosis. CT is an important diagnostic advancement in the field of COPD. Most methods for the evaluation of emphysema are based on the detection and measurement of areas characterised by a density level below a threshold assumed to characterize parenchymal destruction. Methods. Our retrospective study included 47 healthy subjects (65-91 years), 36 never smokers a…

The loss of the beneficial effect of deep inspiration (DI) in COPD is associated with severity of disease

A 15-Year-Old Boy with Anterior Chest Pain, Progressive Dyspnea, and Subcutaneous Emphysema of the Neck

We describe the case of an adolescent who was admitted to the hospital because of sudden occurrence of chest pain, dyspnea and subcutaneous emphysema. On admission, physical examination revealed subcutaneous crepitations in the superior part of the rib cage, and auscultation of the chest showed widespread wheezing. The radiological assessment confirmed the diagnosis of pneumomediastinum and pneumothorax. A follow-up CT scan performed one week after the admission showed almost complete resolution of the radiological alterations. At the following visits, the patient was asymptomatic, but reported to have suffered from frequent episodes of rhinorrea, sneezing, nasal blockage, and sometimes, ch…

Broncoscopia virtuale in pazienti con lesioni endobronchiali stenosanti. Ottimizzazione della tecnica con TC spirale monostrato

PURPOSE: To describe an original protocol for single slice spiral Computed Tomography (CT) virtual bronchoscopy in the evaluation of patients with central airway stenoses and compare the results with fibreoptic bronchoscopy. MATERIALS AND METHODS: Ten patients (4 female and 6 male; age range 22-60 years; mean age 44 years) with endobronchial disease diagnosed by fibreoptic bronchoscopy (8 malignant tumours, 1 benign tumour and 1 fibroid stenosis) underwent virtual bronchoscopy with single slice spiral CT. A panoramic spiral CT scan of the whole chest was first obtained. Once the area of interest had been identified, a new contrast enhanced scan was performed, from bottom to top, with the fo…

The Bronchodilatory effect of deep inspiration (DI) in subjects with pulmonary fibrosis

Valutazione della riduzione della distensibilità delle vie aeree in relazione alla gravità del quadro di broncopneumopatia cronica ostruttiva mediante Tc ad alta risoluzione.

Airway Wall Thickness By HRCT Does Not Affect Airway Distensibility In Asthma And COPD

The usefulness of Sonovue-enhanced pulse-inversion US to assess hepatocellular carcinoma response after percutaneous radiofrequency thermal ablation therapy

Malattie Respiratorie nell’ anziano

Broncoscopia virtuale in pazienti con lesioni endobronchiali stenosanti: ottimizzazione della tecnica con TC spirale monostrato

L’effetto broncodilatatore dell’inspirazione profonda nell’asma

Aspetti con TC ed RM delle cisti peribiliari

Airway distensibility by HRCT decreases with severity of COPD.

Usefulness of SonoVue-enhanced Pulse-Inversion Ultrasonography to Assess Hepatocellular Carcinoma Response after Percutaneous Radiofrequency Thermal Ablation Therapy

La broncoscopia virtuale mediante TC spirale

Studio della deglutizione mediante cineradiografia digitale nei bambini con alterazioni neurologiche: nostra esperienza

Valutazione mediante hrct delle specifiche alterazioni polmonari nelle diverse forme cliniche di sclerosi sistemica

Digital cineradiographic study of swallowing in infants with neurologic disease: Our experience

Airway remodelling assessed by sputum and high resolution computed tomography in asthma and COPD

It is not known whether sputum elastase, metalloproteinase (MMP)-9 and tissue-inhibitor metalloproteinase (TIMP)-1 are related to structural changes of the airways, as assessed by high-resolution computed tomography (HRCT) scan. The relationships between these markers and the magnitude of structural changes of the airways in asthma and chronic obstructive pulmonary disease (COPD) were assessed. Induced sputum and HRCT scan were performed in 30 asthmatics (14 mild and 16 severe) and in 12 patients with COPD. A greater extent of HRCT scan abnormalities was found in COPD than in severe and mild asthmatics. HRCT scan abnormalities correlated with the degree of airway obstruction in COPD and in …

Airway Distensibility by HRCT in COPD Patients

Valori di densità TC nella diagnosi differenziale tra polmone senile ed enfisema

Usefulness of SonoVue-enhanced Pulse-Inversion Ultrasonography to Assess Hepatocellular Carcinoma Response after Percutaneous Radiofrequency Thermal Ablation Therapy

Physical capacity in performing daily activities is reduced in scleroderma patients with early lung involvement

Background and Aims Patients with systemic sclerosis (SSc) often complain reduced capacity at submaximal exercise; conversely, physical capacity in performing daily duties has never been measured in SSc. The aim of this study is to evaluate this performance and its correlates, in patients with SSc compared with healthy controls, in a free-living setting. Methods Twenty-seven outpatients with stable SSc and 11 controls were recruited. Physical activity was assessed by portable multiple sensor device (SenseWear Armband) worn for at least 6 days. Physical activity duration (PAD; in minutes) for non-sedentary activities and physical activity level (PAL = total daily energy/resting energy expend…

Two approaches to assess physical activities of daily life; steps and energy expediture.

Reduced exercise capacity and impaired pulmonary function in patients with scleroderma

A rare case of pedunculated bronchial hemangioma

We describe a rare case of pedunculated endobronchial hemangioma observed in a 60 years old patient complaining of chronic productive cough and accessional dyspnea which had been progressively worsening over 20 years. The lesion was first noticed at fiberoptic bronchoscopy; then computed tomography scan was performed and integrated with tridimensional reconstruction techniques. Pathology showed the picture of a vascular neoplasm, compatible with capillary hemangioma. The lesion was submitted to laser-assisted endoscopic removal in order to relieve the obstruction, leading to remission of symptoms.

Non invasive diagnosis in a case of bronchopulmobary sequestration and proposal of diagnostic algorithm

Assessment of large and small airways wall thickness by HRCT in asthma

Purpose Methods and Materials Results Conclusion References Personal Information

The loss of the beneficial effect of deep inspiration (DI) in COPD is associated with severity of disease

Alterazioni degli effetti broncodilatatori della inspirazione profonda in pazienti con Sclerosi Sistemica

Valutazione della reattività vascolare in pazienti sclerodermici mediante ultrasonografia (US) con mezzo di contrasto (MDC).

The bronchodilatatory ability of deep inspiration Is impaired in scleroderma.

Correlazioni radiologico-funzionali nell' inquadramento delle pneumopatie croniche diffuse

Applicazione dell' HRCT nella valutazione dello spessore delle vie aeree nella BPCO

Pulmonary functional and radiological correlations of nutritional status and physical activity in systemic sclerosis

Purpose Methods and Materials Results Conclusion References Personal Information

The attenuation of the bronchodilatory effect of deep inspiration(DI) is associated with the degree of emphisema

HRCT and scleroderma: semiquantitative evaluation of lung damage and functional abnormalities.

This study sought to validate the Warrick score in the assessment of lung involvement in systemic sclerosis (SSc) and correlate the results with functional abnormalities. In addition, we propose the use of high resolution computed tomography (HRCT) indices of alveolitis and fibrosis to discriminate between different stages of the disease.Thirty-one patients with SSc (16 with the diffuse form and 15 with the limited form) underwent functional and HRCT evaluations of the lung. The semiquantitative evaluation of radiological involvement, as proposed by Warrick, provides a score for each lesion based on the severity and the extent of the pulmonary damage. In addition to the total score, indices…

Il polmone senile

The airway response to deep inspirations decreases with COPD severity and is associated with airway distensibility assessed by computed tomography.

In patients with mild chronic obstructive pulmonary disease (COPD), the effect of deep inspirations (DIs) to reverse methacholine-induced bronchoconstriction is largely attenuated. In this study, we tested the hypothesis that the effectiveness of DI is reduced with increasing disease severity and that this is associated with a reduction in the ability of DI to distend the airways. Fifteen subjects [Global Initiative for Chronic Obstructive Lung Disease (GOLD) stage I–II: n = 7; GOLD stage III–IV: n = 8] underwent methacholine bronchoprovocation in the absence of DI, followed by DI. The effectiveness of DI was assessed by their ability to improve inspiratory vital capacity and forced expira…

Lung hyperinflation in COPD attenuates airway distension by deep inspiration (DI) measured with HRCT

Airway distensibility by HRCT in asthmatics and COPD with comparable airway obstruction.

Introduction: Decreased airway distensibility (AD) in response to deep inspirations, as assessed by HRCT, has been associated with the severity of asthma and COPD. Aims: The current study was designed to compare the magnitude of AD by HRCT in individuals with asthma and COPD with comparable degrees of bronchial obstruction, and to explore factors that may influence it. Results: We enrolled a total of 12 asthmatics (M/F:7/5) and 8 COPD (7/1) with comparable degree of bronchial obstruction (FEV1% predicted mean±SEM: 69.1 ± 5.2% and 61.2 ± 5.0%, respectively; p = 0.31). Each subject underwent chest HRCT at FRC and at TLC. A total of 701 airways (range 20 to 38 airway per subject; 2.0 to 23.1 m…

Nutritional evaluation and physical activity in scleroderma patients