Ad-Hoc Segmentation Pipeline for Microarray Image Analysis

Microarray is a new class of biotechnologies able to help biologist researches to extrapolate new knowledge from biological experiments. Image Analysis is devoted to extrapolate, process and visualize image information. For this reason it has found application also in Microarray, where it is a crucial step of this technology (e.g. segmentation). In this paper we describe MISP (Microarray Image Segmentation Pipeline), a new segmentation pipeline for Microarray Image Analysis. The pipeline uses a recent segmentation algorithm based on statistical analysis coupled with K-Means algorithm. The Spot masks produced by MISP are used to determinate spots information and quality measures. A software …

Digital Mosaic Frameworks - an overview

Art often provides valuable hints for technological innovations especially in the field of Image Processing and Computer Graphics. In this paper we survey in a unified framework several methods to transform raster input images into good quality mosaics. For each of the major different approaches in literature the paper reports a short description and a discussion of the most relevant issues. To complete the survey comparisons among the different techniques both in terms of visual quality and computational complexity are provided.

Medical Imaging Applications: Three Case Studies

Adaptive Techniques for Microarray Image Analysis with Related Quality Assessment

We propose novel techniques for microarray image analysis. In particular, we describe an overall pipeline able to solve the most common problems of microarray image analysis. We pro- pose the microarray image rotation algorithm (MIRA) and the statis- tical gridding pipeline (SGRIP) as two advanced modules devoted to restoring the original microarray grid orientation and to detecting, the correct geometrical information about each spot of input mi- croarray, respectively. Both solutions work by making use of statis- tical observations, obtaining adaptive and reliable information about each spot property. They improve the performance of the microarray image segmentation pipeline (MISP) we rec…