0000000000920611

AUTHOR

M. Pilar García-pardo

showing 2 related works from this author

Cannabidiol Treatment Might Promote Resilience to Cocaine and Methamphetamine Use Disorders: A Review of Possible Mechanisms

2019

Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors describe the scarce preclinical and human research about the actions of CBD on the effects of stimulant drugs, mainly cocaine and methamphetamine (METH). Additionally, the possible mechanisms underlying the therapeutic potential of CBD on stimulant use disorders are reviewed. CBD has reversed toxicity and seizures induced by cocaine, behavioural sensitization induced by amphetamines, motivation to self-administer cocaine and METH, context- …

medicine.medical_treatmentPharmaceutical ScienceCravingReviewPharmacologyAnalytical ChemistryHealth Risk Behaviorschemistry.chemical_compoundcannabidiol0302 clinical medicineDrug DiscoveryMedicineratrewardmedia_commonResilience PsychologicalMethamphetamineconditioned place preferenceSubstance Withdrawal SyndromeObservational Studies as TopicChemistry (miscellaneous)Molecular Medicineaddictionmedicine.symptomSelf-administrationself-administrationmedicine.drugmicemedia_common.quotation_subjectAmphetamine-Related DisorderscocaineContext (language use)lcsh:QD241-441Cocaine-Related Disorders03 medical and health scienceslcsh:Organic chemistryAnimalsHumansPhysical and Theoretical Chemistrymethamphetaminebusiness.industryAddictionOrganic ChemistryMeth-Conditioned place preferencedigestive system diseasesreinstatement030227 psychiatryStimulantchemistrybusiness030217 neurology & neurosurgeryMolecules
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Cannabidiol treatment might promote resilience to cocaine and methamphetamine use disorders: A review of possible mechanisms

2019

Currently, there are no approved pharmacotherapies for addiction to cocaine and other psychostimulant drugs. Several studies have proposed that cannabidiol (CBD) could be a promising treatment for substance use disorders. In the present work, the authors describe the scarce preclinical and human research about the actions of CBD on the effects of stimulant drugs, mainly cocaine and methamphetamine (METH). Additionally, the possible mechanisms underlying the therapeutic potential of CBD on stimulant use disorders are reviewed. CBD has reversed toxicity and seizures induced by cocaine, behavioural sensitization induced by amphetamines, motivation to self-administer cocaine and METH, context- …

digestive system diseases
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