0000000000922902
AUTHOR
C Messa
A Study of Choline and Standard Uptake Value Correlation in Discriminating IDC from ILC.
Genomic and Proteomic Integrated Approach to Study Breast Cancer: Differences in Patients negative and Positive to 18F-FDG PET Screening
Breast cancer rather presents distinct subtypes associated with different clinical outcomes. Understanding this heterogeneity is a key factor for the development of targeted preventative and therapeutic interventions (Rakha et al 2008). 18Ffluoro- 2-deoxy-D-glucose Positron Emission Tomography (18F-FDG PET) has been evaluated in breast cancer to characterize primary tumors, lymph node staging and patients follow-up after surgery, chemotherapy and/or external radiotherapy (Lind et al 2004). PET is a molecular imaging technique sensitive to functional or metabolic changes in tissues. Since functional changes precede anatomical changes, FDG PET has the capability to detect viable tumor tissue …
Correlation between SUV with Partial Volume Correction and choline in breast cancer.
Inflammatory Response to a High Radiation Dose in Breast Cancer
Background: Radiation therapy (RT) is an essential treatment modality used for breast cancer (BC) care. Radiations can stimulate the immune system via the early activation of cytokine cascades, which can greatly affect cellular radio-sensitivity. Our aim is to analyze inflammatory response induced by high ionizing radiation (IR) doses, generated by intraoperative radiotherapy (IORT) treatment, to identify several potential targets that may influence cell radio-response. Methods: MCF10, MCF7 and MDA-MB231 BC cell lines have been exposed to high IR (23 Gray and 9 Gray), delivered by IORT treatments. Conditioned media (CM) were assayed at the time points: 0’, 30’, 1, 3, 6, 24, 48, and 72 hours…