0000000000924319
AUTHOR
A. Garcia-raso
Unsaturated carboxylic acid dienolates. Addition to substituted cyclohexanones. Inverted kinetic and thermodynamic stereoselectivities.
Abstract Addition of the lithium dienolate derived from crotonic acid to monosubstituted cyclohexanones occurs through the α and γ carbon atoms of the dienolate in the cold and on heating, respectively. For any regioselectivity, equatorial approach is found under kinetic conditions, but equilibration favours products from axial attack and selectivity may be inverted.
Impact of sex, age, and risk factors for venous thromboembolism on the initial presentation of first isolated symptomatic acute deep vein thrombosis
Abstract Background and aims Sex-specific differences exist for the initial presentation of acute venous thromboembolism (VTE): men are more likely to present with proximal deep vein thrombosis (DVT) in the lower limbs (versus pulmonary embolism [PE] or isolated distal DVT [IDDVT]) than women. We studied in detail the influence of sex, age, and VTE risk factors on the initial presentation of IDDVT versus proximal DVT. Methods A total of 24,911 patients with a first episode of objectively diagnosed acute symptomatic lower-limb DVT (without symptomatic PE) were enrolled in RIETE (years 2000–2017) and included in the present analysis. Results A total of 4266 (17.1%) patients had IDDVT. No tren…
CCDC 137960: Experimental Crystal Structure Determination
Related Article: A.Garcia-Raso, J.J.Fiol, S.Rigo, A.Lopez-Lopez, E.Molins, E.Espinosa, E.Borras, G.Alzuet, J.Borras, A.Castineiras|2000|Polyhedron|19|991|doi:10.1016/S0277-5387(00)00355-7
CCDC 137959: Experimental Crystal Structure Determination
Related Article: A.Garcia-Raso, J.J.Fiol, S.Rigo, A.Lopez-Lopez, E.Molins, E.Espinosa, E.Borras, G.Alzuet, J.Borras, A.Castineiras|2000|Polyhedron|19|991|doi:10.1016/S0277-5387(00)00355-7
CCDC 137958: Experimental Crystal Structure Determination
Related Article: A.Garcia-Raso, J.J.Fiol, S.Rigo, A.Lopez-Lopez, E.Molins, E.Espinosa, E.Borras, G.Alzuet, J.Borras, A.Castineiras|2000|Polyhedron|19|991|doi:10.1016/S0277-5387(00)00355-7