Survivin detection in saliva samples from patients with oral squamous cell carcinoma

Oral Lichen Planus: a new experimental therapeutic protocol by means of oxygen-ozone mixture injection.

Clinical effectiveness of platelet concentrates for periodontal regeneration

Osteonecrosis of the jaw related to everolimus and bisphosphonate: a unique case report?

Osteonecrosis of the jaw (ONJ) is a rare but serious lesion of the jaw, characterized mainly by exposed necrotic bone;it is related to various drugs, usually used for treating patients with advanced malignancies. Drugs implicated in ONJ are: nitrogen-containing bisphosphonates (NBPs), denosumab, anti-angiogenic drugs (e.g bevacizumab, sunitinib,sorafenib) and the selective mammalian target of rapamycin mTOR, everolimus. Previous data regarding the combining of NBPs with antiangiogenic agents conflict with some reports (indicating a similar risk of ONJ compared with the use of NBPs alone1); other reports show significantly higher rates (18% vs 1% with NBPs alone) of the incidence of ONJ2. Th…

Oral lesions as primary manifestations of acute agranulocytosis related to metamizole: a case report

New perspectives in medical approach to therapy of head and neck squamous cell carcinoma

Head and neck cancer is the eighth most common cause of cancer death worldwide. Its incidence varies widely among different regions. In North America and the European Union, head and neck cancer accounts for 3% to 4% of all cancer diagnoses. Conversely, in Southeast Asia and Africa, head and neck cancer accounts for approximately 8% to 10% of all cancers1. Although the incidence of head and neck cancers has decreased slightly from 1975 to 2002 in the United States5, approximately 46 000 new cases are still expected in 2007 alone. Even if surgery and radiotherapy have remained the core therapy in squamous cell carcinoma of the head and neck (HNSCC). Radiotherapy following surgery was the sta…

Interventions for treating osteonecrosis of the jaw stage III: may conservative surgical management be a viable option?

Dual localization of oral Kaposi’s sarcoma in HIV-negative patient: a rare case report

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The association between periodontal diseases and cardiovascular diseases: A narrative review

A strange “butterly-like” ulcer of the palate. May be it the results of an underlying trombotic event in a predisposed patient?

Occurrence of oro-facial malformations in a tertiary center hospital of Southern Italy: retrospective study on ten thousand newborns

Congenital anomalies (CA) are one of the major cause of infant mortality and childhood morbitity, affecting 2-3% of all babies. Approximately 1% of these newborns have syndromes or multiple anomalies; Cranio-facial anomalies are often a component part of these pathologies. Several newborns with cranio-facial anomalies are affected by syndromes composed of multiple malformations thought to be etiologically and/ or pathogenetically related. One of the most frequent sign of these syndromes is the cleft lip and/or cleft palate. It is estimated that 30% of cleft cases are syndromic and conversely, therefore, approximately 70% are non-syndromic. Oral clefts are among the most widely known and com…

A case of osteonecrosis of the jaws in epidermolysis bullosa patient treated with rituximab.

We report a case of a patient with EBA, who developed ONJ after Rituximab treatment.