0000000000931703

AUTHOR

Stuart A. West

showing 2 related works from this author

Sociovirology: Conflict, Cooperation, and Communication among Viruses

2017

Viruses are involved in various interactions both within and between infected cells. Social evolution theory offers a conceptual framework for how virus-virus interactions, ranging from conflict to cooperation, have evolved. A critical examination of these interactions could expand our understanding of viruses and be exploited for epidemiological and medical interventions.

0301 basic medicineKnowledge managementCoinfectionbusiness.industryviruses030106 microbiologyPsychological interventionBiologyMicrobiologyArticleCritical examination3. Good health03 medical and health sciences030104 developmental biologyConceptual frameworkVirus DiseasesVirologyHost-Pathogen InteractionsHumansParasitologySocial evolutionbusinessSignal TransductionVirus Physiological PhenomenaCell Host & Microbe
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The evolution of collective infectious units in viruses

2019

Viruses frequently spread among cells or hosts in groups, with multiple viral genomes inside the same infectious unit. These collective infectious units can consist of multiple viral genomes inside the same virion, or multiple virions inside a larger structure such as a vesicle. Collective infectious units deliver multiple viral genomes to the same cell simultaneously, which can have important implications for viral pathogenesis, antiviral resistance, and social evolution. However, little is known about why some viruses transmit in collective infectious units, whereas others do not. We used a simple evolutionary approach to model the potential costs and benefits of transmitting in a collect…

Viral pathogenesisviruseseducationGenome ViralBiologyVirus ReplicationGenomebehavioral disciplines and activitiesArticleEvolution Molecular03 medical and health sciences0302 clinical medicine030304 developmental biology0303 health sciencesVirus AssemblyAntiviral resistanceVirionDefective VirusesModels TheoreticalVirologyViral replicationViral genomesVirus Diseasespopulation characteristicsRNA Viral030217 neurology & neurosurgery
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