0000000000932103

AUTHOR

Giuseppe Stampone

showing 2 related works from this author

Improvement of a rapid direct blood culture microbial identification protocol using MALDI-TOF MS and performance comparison with SepsiTyper kit

2018

Fast diagnosis of pathogens is critical to guarantee the most adequate therapy for infections; bacterial culture methods, which constitute the actual gold standard, are precise and sensitive but rather slow. Today, new methods have been made available to enable faster diagnosis, with the Matrix-Assisted Laser Desorption Ionization-Time Of Flight Mass Spectrometry (MALDI-TOF MS) technique being the most promising. Even if simpler and faster than traditional bacterial culture methods, analysis of positive blood cultures via MALDI-TOF MS requires a preliminary extraction process of samples. In this study, we compared two extraction protocols for bacterial identification directly from positive …

0301 basic medicineMicrobiology (medical)Time FactorsComputer science030106 microbiologyBacteremiaClinical diagnostic laboratorySensitivity and SpecificityMicrobiology03 medical and health sciencesSpecies SpecificitymedicineHumansBlood cultureOverall performanceMolecular BiologyProtocol (science)Bacteriological TechniquesChromatographyBacteriamedicine.diagnostic_testDiagnostic Tests RoutineGold standard (test)Matrix-assisted laser desorption/ionizationIdentification (information)Blood CulturePathogens identificationSpectrometry Mass Matrix-Assisted Laser Desorption-IonizationPerformance comparisonCosts and Cost AnalysisGenus and species identificationMatrix- assisted laser desorption ionization time of flight mass spectrometryJournal of Microbiological Methods
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Innovative and Integrated Strategies: Case Studies

2017

In this chapter, case studies related to biodeterioration, bioaerosol, biocide and biocleaning are reported. The aim is highlighting the role of biology and biotechnology tools for the preventive conservation of organic and inorganic artifacts, understanding how traditional as well as innovative methods can help the conservationists to develop integrated strategies considering works of art/environment/ humans as a dynamic system. Particularly, based on the experience acquired during the researches of Laboratory of Biology and Biotechnology for Cultural Heritage (LaBBCH), the authors suggest several approaches to reveal and identify biological systems able to induce biodeterioration of cultu…

0301 basic medicineBiochemistry Genetics and Molecular Biology (all)Immunology and Microbiology (all)Cultural assetBioactive molecules010401 analytical chemistryIndoor bioaerosolSettore BIO/05 - Zoologia01 natural sciencesSocial Sciences (all)0104 chemical sciencesCultural heritage03 medical and health sciences030104 developmental biologyRisk analysis (engineering)Settore BIO/03 - Botanica Ambientale E Applicata
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