SYNTHESIS OF 2-TRIAZENO-PYRROLO-PYRIDINES A NEW CLASS OF TRIAZENES WITH ANTITUMOR ACTIVITY

2010

7-Azaindole-fused heterocycles with antitumor activity

2011

3-CHLOROETHYL-PYRROLO[2,1-D][1,2,3,5]TETRAZINES: SYNTHESIS AND ANTITUMOR ACTIVITY

2011

Understanding Factors Associated With Psychomotor Subtypes of Delirium in Older Inpatients With Dementia

2020

Objectives Few studies have analyzed factors associated with delirium subtypes. In this study, we investigate factors associated with subtypes of delirium only in patients with dementia to provide insights on the possible prevention and treatments. Design This is a cross-sectional study nested in the "Delirium Day" study, a nationwide Italian point-prevalence study. Setting and participants Older patients admitted to 205 acute and 92 rehabilitation hospital wards. Measures Delirium was evaluated with the 4-AT and the motor subtypes with the Delirium Motor Subtype Scale. Dementia was defined by the presence of a documented diagnosis in the medical records and/or prescription of acetylcholine…

Condensed azaindole with antitumor activity

2011

Photochemotherapeutic heterocyclic agents having antiproliferative and antineoplastic activity

2012

The present invention concerns the synthesis of new analogs of angelicins, pyrrolo[3,2-h]quinoline, for the treatment of pathologie having hyperproliferative character including those having neoplastic nature. The treatment is based on the combined action of pyrrolo[3,2-h]quinolines and UV-A light, through a clinical approach defined as PUVA (psoralen-UVA light). The most important feature of these compounds is that they exert their remarkable phototoxicity without any DNA damage, which is the main origin of the side effects of the PUVA therapy