0000000000936354
AUTHOR
Fritz Lekschas
Additional file 1 of MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
Literature-curated marker genes. This file includes marker genes collected from the literature. (104KB PDF)
Additional file 5 of MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
Primer sequences. This file includes the list of all primer sequences used by PCR. (55.7KB PDF)
Additional file 2 of MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
Plots of Precision/Recall comparing our method to t -test. This file includes Plots of Precision/Recall comparing MGFM to t-test. (462KB PDF)
Additional file 4 of MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
Description of the predicted marker genes. (126KB PDF)
MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
Background Identification of marker genes associated with a specific tissue/cell type is a fundamental challenge in genetic and cell research. Marker genes are of great importance for determining cell identity, and for understanding tissue specific gene function and the molecular mechanisms underlying complex diseases. Results We have developed a new bioinformatics tool called MGFM (Marker Gene Finder in Microarray data) to predict marker genes from microarray gene expression data. Marker genes are identified through the grouping of samples of the same type with similar marker gene expression levels. We verified our approach using two microarray data sets from the NCBI’s Gene Expression Omn…
Additional file 3 of MGFM: a novel tool for detection of tissue and cell specific marker genes from microarray gene expression data
Gel electrophoresis images. This file includes the gel electrophoresis images (Figures S1â S11). (981KB PDF)