0000000000936731

AUTHOR

S. Ryan

showing 10 related works from this author

Clinical presentation of patients with suspected obstructive sleep apnea and self-reported physician-diagnosed asthma in the ESADA cohort.

2018

Obstructive sleep apnea (OSA) and asthma are often associated and several studies suggest a bidirectional relationship between asthma and OSA. This study analyzed the characteristics of patients with suspected OSA from the European Sleep Apnea Database according to presence/absence of physician-diagnosed asthma. Cross-sectional data in 16,236 patients (29.1% female) referred for suspected OSA were analyzed according to occurrence of physician-diagnosed asthma for anthropometrics, OSA severity and sleepiness. Sleep structure was assessed in patients studied by polysomnography (i.e. 48% of the sample). The prevalence of physician-diagnosed asthma in the entire cohort was 4.8% (7.9% in women, …

AdultMaleobesitymedicine.medical_specialtyCognitive NeurosciencePolysomnographyPopulationPolysomnographySettore MED/10 - Malattie Dell'Apparato Respiratoriota3111Cohort Studies03 medical and health sciencesBehavioral Neuroscience0302 clinical medicineobstructive sleep apnea ; asthma ; ESADA cohortInternal medicineEpidemiologygenderMedicineHumansProspective StudieseducationPhysician's RoleAsthmaAgededucation.field_of_studySleep Apnea Obstructivemedicine.diagnostic_testbusiness.industryta1184sleep-disordered breathingSleep apneaGeneral MedicineMiddle Agedmedicine.diseaseObesityAsthmarespiratory tract diseasesObstructive sleep apneaEuropeCross-Sectional Studies030228 respiratory systemCohortepidemiologyFemaleSelf Reportbusiness030217 neurology & neurosurgeryJournal of sleep research
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The Gaia-ESO Public Spectroscopic Survey

2012

The Gaia-ESO Public Spectroscopic Survey has begun and will obtain high quality spectroscopy of some 100000 Milky Way stars, in the field and in open clusters, down to magnitude 19, systematically covering all the major components of the Milky Way. This survey will provide the first homogeneous overview of the distributions of kinematics and chemical element abundances in the Galaxy. The motivation, organisation and implementation of the Gaia-ESO Survey are described, emphasising the complementarity with the ESA Gaia mission. Spectra from the very first observing run of the survey are presented.

spectroscopy stars kinematics abundancesSettore FIS/05 - Astronomia E AstrofisicaAstrophysics::Instrumentation and Methods for AstrophysicsAstrophysics::Solar and Stellar AstrophysicsAstrophysics::Earth and Planetary AstrophysicsAstrophysics::Cosmology and Extragalactic AstrophysicsAstrophysics::Galaxy Astrophysics
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Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: longitudinal data from the ESADA coho…

2018

The effect of positive airway pressure treatment on weight and markers of central obesity in patients with obstructive sleep apnea remains unclear. We studied the change in body weight and anthropometric measures following positive airway pressure treatment in a large clinical cohort. Patients with obstructive sleep apnea with positive airway pressure treatment from the European Sleep Apnea Database registry (n = 1, 415, 77% male, age 54 ± 11 [mean ± SD] years, body mass index 31.7 ± 6.4 kg/m2, apnea–hypopnea index 37 ± 24 n per hr, Epworth Sleepiness Scale 10.2 ± 5.0) were selected. Changes in body mass index and neck/waist/hip circumferences at baseline and at follow-up visit were analyse…

Data AnalysisMaleTime FactorsExcessive daytime sleepinessWeight Gainexcessive daytime sleepineBody Mass IndexCohort StudiesBehavioral Neuroscience0302 clinical medicinePositive airway pressureMedicineLongitudinal StudiesProspective Studiesobstructive sleep apneaSleep Apnea ObstructiveContinuous Positive Airway PressureEpworth Sleepiness ScaleSleep apneaGeneral MedicineMiddle Agedweight ; central obesity ; positive airway pressure ; obstructive sleep apnea ; ESADA cohortEuropeObesity AbdominalCardiologyFemaleWaist Circumferencemedicine.symptomAdultmedicine.medical_specialtyCognitive NeuroscienceSettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicineHumanspositive airway pressureAgedcentral obesitybusiness.industryBody Weightbody weight central obesity excessive daytime sleepiness obstructive sleep apnea positive airway pressureta3121medicine.diseaseObesityrespiratory tract diseasesObstructive sleep apnea030228 respiratory systemHuman medicinebusinessBody mass indexWeight gain030217 neurology & neurosurgery
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Impact of clinical phenotypes on management and outcomes in European atrial fibrillation patients: a report from the ESC-EHRA EURObservational Resear…

2021

Abstract Background Epidemiological studies in atrial fibrillation (AF) illustrate that clinical complexity increase the risk of major adverse outcomes. We aimed to describe European AF patients’ clinical phenotypes and analyse the differential clinical course. Methods We performed a hierarchical cluster analysis based on Ward’s Method and Squared Euclidean Distance using 22 clinical binary variables, identifying the optimal number of clusters. We investigated differences in clinical management, use of healthcare resources and outcomes in a cohort of European AF patients from a Europe-wide observational registry. Results A total of 9363 were available for this analysis. We identified three …

RegistrieResearch Reportmedicine.medical_specialtyMajor adverse outcomeCardiovascular risk factorsCluster analysisRisk FactorsInternal medicineClinical phenotypeAtrial FibrillationEpidemiologyHumansMedicineRegistriesCluster analysiAtrial fibrillation; Clinical management; Clinical phenotypes; Cluster analysis; Major adverse outcomes; Humans; Phenotype; Registries; Research Report; Risk Factors; Atrial FibrillationClinical managementbusiness.industryProportional hazards modelRisk FactorHazard ratioRAtrial fibrillationClinical phenotypesMajor adverse outcomesGeneral Medicinemedicine.diseaseAtrial fibrillationConfidence intervalPhenotypeCohortMedicineObservational studybusinessResearch ArticleHumanBMC Medicine
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Worldwide comparison of ovarian cancer survival: Histological group and stage at diagnosis (CONCORD-2)

2016

Abstract Objective Ovarian cancer comprises several histological groups with widely differing levels of survival. We aimed to explore international variation in survival for each group to help interpret international differences in survival from all ovarian cancers combined. We also examined differences in stage-specific survival. Methods The CONCORD programme is the largest population-based study of global trends in cancer survival, including data from 60 countries for 695,932 women (aged 15–99years) diagnosed with ovarian cancer during 1995–2009. We defined six histological groups: type I epithelial, type II epithelial, germ cell, sex cord-stromal, other specific non-epithelial and non-sp…

0301 basic medicineOncologySettore MED/42 - Igiene Generale E Applicata0302 clinical medicinemorphology80 and overStage (cooking)Aged 80 and overOvarian Neoplasmseducation.field_of_studyepidemiology; histology; morphology; ovarian cancer; stage; survival; Adolescent; Adult; Aged; Aged 80 and over; Female; Humans; Middle Aged; Neoplasm Staging; Ovarian Neoplasms; Oncology; Obstetrics and GynecologyObstetrics and Gynecologyepidemiology; histology; morphology; ovarian cancer; stage; survivalMiddle AgedTransitional cell carcinomaovarian cancerOncology030220 oncology & carcinogenesisClear cell carcinomaepidemiologyFemaleHumanAdultmedicine.medical_specialtyAdolescentPopulationSocio-culturalesurvivalArticlehistology03 medical and health sciencesInternal medicinemedicineHumansovarian cancer epidemiology survival stage morphology histologyeducationepidemiology ; histology ; morphology ; ovarian cancer ; stage ; survivalCancer stagingAgedNeoplasm StagingGynecologybusiness.industryOvarian NeoplasmCancermedicine.diseasestageCancer registry030104 developmental biologyOvarian cancerbusiness
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Insomnia symptoms combined with nocturnal hypoxia associate with cardiovascular comorbidity in the European sleep apnea cohort (ESADA)

2018

WOS: 000482433800011

AdultMalemedicine.medical_specialtyInsomniaNeurologyComorbiditySettore MED/10 - Malattie Dell'Apparato RespiratorioNocturnalHypoxemiaHypoxemia03 medical and health sciences0302 clinical medicineRisk FactorsSleep Initiation and Maintenance DisordersInternal medicinemental disordersPrevalenceInsomniaHumansMedicineHypoxiaSleep Apnea Obstructivebusiness.industrySleep Breathing Physiology and Disorders • Original ArticleSleep apneaSleep apneaMiddle AgedCardiovascular disease ; Comorbidity ; Hypoxemia ; Insomnia ; Phenotype ; Sleep apnea.Hypoxia (medical)Cardiovascular diseasemedicine.diseaseComorbidityCircadian Rhythmnervous system diseasesEuropePhenotype030228 respiratory systemOtorhinolaryngologyCardiovascular DiseasesCohortFemaleHuman medicineNeurology (clinical)medicine.symptombusiness030217 neurology & neurosurgerySleep and Breathing
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Hyperlipidaemia prevalence and cholesterol control in obstructive sleep apnoea: Data from the European sleep apnea database (ESADA)

2019

Abstract.Gunduz C, Basoglu OK, Hedner J, et al; onbehalf of the European Sleep Apnoea Databasecollaborators (Biruni University; Ege University;Gothenburg University; Sahlgrenska UniversityHospital; University of Palermo; CNR Institute ofBiomedicine and Molecular Immunology; St. AdolfStift; Hospital de Santa Maria; University of Crete;Antoine-Beclere Hospital; G. PapanikolaouHospital; Institute of Tuberculosis and LungDiseases; University Hospital Brno; St. Ann’sUniversity Hospital; Universite ́ Grenoble Alpes)Hyperlipidaemia prevalence and cholesterolcontrol in obstructive sleep apnoea: Data from theEuropean sleep apnea database (ESADA).J InternMed2019;286: 676–688.Background and objective.…

Male0301 basic medicine[SDV]Life Sciences [q-bio]PolysomnographyHyperlipidemiasSettore MED/10 - Malattie Dell'Apparato Respiratorio030204 cardiovascular system & hematologycomputer.software_genre03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusPrevalenceInternal MedicineHumansMedicinecholesterol ; hyperlipidaemia ; hypoxia ; obesity ; sleep apnoea.ObesitySleep Apnea ObstructiveDatabasehyperlipidaemiahypoxiabusiness.industryConfoundingcholesterolSleep apneaOdds ratioMiddle Agedmedicine.diseaseObesityrespiratory tract diseases[SDV] Life Sciences [q-bio]EuropeCross-Sectional Studies030104 developmental biologyQuartileCardiovascular DiseasesCohortFemaleHuman medicinebusinesssleep apnoeaBody mass indexcomputer
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Cancer prevalence is increased in females with sleep apnoea: data from the ESADA study

2019

[No abstract available]

MaleobesityLetterDatabases FactualDownload[SDV]Life Sciences [q-bio]cigarette smokingPolysomnographycancer riskdisease burdenapnea hypopnea indexsleep disordered breathingstudy design0302 clinical medicinepolysomnographyRisk FactorsNothingcancer diagnosisNeoplasmsmiddle agedgenderPrevalence030212 general & internal medicineSleep studyobstructive sleep apneaSleep Apnea Obstructiveeducation.field_of_studyanthropometryquantitative analysismedicine.diagnostic_testadultrisk assessmentclinical trialcohort analysisprostate cancerpulse oximetry[SDV] Life Sciences [q-bio]Europenot availablecomorbidityagedfemalewaist hip ratiocolon cancerpriority journalrisk factorfactual databasedisease severitycerebrovascular accidentPulmonary and Respiratory Medicinemedicine.medical_specialtyalcohol consumptionintermittent hypoxiaPopulationMEDLINElymphomaSettore MED/10 - Malattie Dell'Apparato Respiratoriomalignant neoplasmcancer growth03 medical and health sciencesmelanomamedicinecancercross-sectional studyHumanscontrolled studyhumaneducationCancer prevalencehypoxiabusiness.industrystatistical modelConflict of interestpredictionmajor clinical studybody massoxygen saturationlung cancermulticenter studyCross-Sectional StudiesLogistic Modelsage030228 respiratory systemdisease severity assessmentFamily medicineoxygen desaturation indexhead and neck cancerHuman medicinebusinessneoplasmEuropean Respiratory Journal
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Obstructive sleep apnoea independently predicts lipid levels: Data from the European Sleep Apnea Database

2018

Background and objective: Obstructive sleep apnoea (OSA) and dyslipidaemia are independent risk factors for cardiovascular disease. This study investigates the association between OSA and plasma lipid concentrations in patients enrolled in the European Sleep Apnea Database (ESADA) cohort. Methods: The cross-sectional analysis included 8592 patients without physician-diagnosed hyperlipidaemia or reported intake of a lipid-lowering drug (age 50.1 ± 12.7 years, 69.1% male, BMI: 30.8 ± 6.6 kg/m2, mean apnoea–hypopnoea index (AHI): 25.7 ± 25.9 events/h). The independent relationship between measures of OSA (AHI, oxygen desaturation index (ODI), mean and lowest oxygen saturation) and lipid profil…

MaleobesityDatabases Factualcholesterol dyslipidemia hypoxia obesity sleep apnoeaGastroenterologyCohort Studieschemistry.chemical_compound0302 clinical medicineRisk FactorsHypolipidemic AgentsOxygen saturation (medicine)Sleep Apnea Obstructivemedicine.diagnostic_testSleep apneaMiddle AgedEuropeQuartileCardiovascular DiseasesCohortFemalelipids (amino acids peptides and proteins)AdultPulmonary and Respiratory Medicinemedicine.medical_specialtySettore MED/10 - Malattie Dell'Apparato Respiratorio03 medical and health sciencesInternal medicinemedicineHumansTriglyceridesDyslipidemiashypoxiaCholesterolbusiness.industryCholesterol HDLdyslipidemiacholesterolCholesterol LDLta3121medicine.diseaseObesitynervous system diseasesrespiratory tract diseasesCross-Sectional Studies030228 respiratory systemchemistryLipid profilebusinesssleep apnoea030217 neurology & neurosurgeryDyslipidemiaRespirology
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Worldwide comparison of survival from childhood leukaemia for 1995–2009, by subtype, age, and sex (CONCORD-2): a population-based study of individual…

2017

BACKGROUND: Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia. METHODS: Cancer registries participating in CONCORD were asked to submit tumour registrations for all children aged 0-14 years who were diagnosed with leukaemia between Jan 1, 1995, and Dec 31, 2009, and followed up until Dec 31, 2009. Haematological malignancies were defined by morphology codes in the International Classification of Diseases for …

childhood leukaemiaCancer registrieleukemiacancerchildhood cancerSocio-culturaleHematologySettore MED/42 - Igiene Generale E ApplicataHematology childhood leukaemia cancer survivalcancer survival
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