0000000000949933

AUTHOR

Jorge Herrera

showing 3 related works from this author

Copper-catalysed enantioselective Michael addition of malonic esters to β-trifluoromethyl-α,β-unsaturated imines

2017

[EN] Copper triflate-BOX complexes catalyse the enantioselective conjugate addition of methyl malonate to beta-trifluoromethyl-alpha,beta-unsaturated imines to give the corresponding enamines bearing a trifluoromethylated stereogenic centre with good yields, and diastereo- and enantioselectivities. The usefulness of the method has been shown with the synthesis of optically active beta-trifluoromethyl delta-amino esters and optically active trifluoromethyl piperidones.

Trifluoromethyl010405 organic chemistryChemistryOrganic ChemistryEnantioselective synthesischemistry.chemical_elementOptically active010402 general chemistry01 natural sciencesBiochemistryCopper0104 chemical sciencesStereocenterchemistry.chemical_compoundCatàlisiMethyl malonateFISICA APLICADAMichael reactionOrganic chemistryPhysical and Theoretical ChemistryQuímica orgànicaConjugateOrganic & Biomolecular Chemistry
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CCDC 1535017: Experimental Crystal Structure Determination

2017

Related Article: Miguel Espinosa, Jorge Herrera, Gonzalo Blay, Luz Cardona, M. Carmen Muñoz, José R. Pedro|2017|Org.Biomol.Chem.|15|3849|doi:10.1039/C7OB00595D

Space GroupCrystallographydimethyl (SE)-(111-trifluoro-4-(((4-methylphenyl)sulfonyl)amino)-4-phenylbut-3-en-2-yl)propanedioateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1535016: Experimental Crystal Structure Determination

2017

Related Article: Miguel Espinosa, Jorge Herrera, Gonzalo Blay, Luz Cardona, M. Carmen Muñoz, José R. Pedro|2017|Org.Biomol.Chem.|15|3849|doi:10.1039/C7OB00595D

Space GroupCrystallographyCrystal System(EE)-4-methyl-N-(444-trifluoro-1-phenylbut-2-en-1-ylidene)benzene-1-sulfonamideCrystal StructureCell ParametersExperimental 3D Coordinates
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