0000000000949982

AUTHOR

Ignacio Alcalde

showing 2 related works from this author

Could structural changes in the retinal layers be a new biomarker of mental disorders? A systematic review and thematic synthesis.

2019

It has recently been suggested that alterations of the layers of the retina could be a biomarker of specific mental disorders since they originate in the same embryonic layer as the brain and both are interconnected through the optic nerve. The purpose of this article is to offer a systematic review of the literature and a thematic synthesis on the current state of the alterations of the retina layers identified by optical coherence tomography in patients with schizophrenia, bipolar disorder and major depression. For this purpose, we performed a bibliographic search, a systematic review of the studies and a thematic synthesis of the reported findings. Patients with schizophrenia have more a…

Bipolar DisorderNerve fiber layerRetina03 medical and health sciences0302 clinical medicinemental disordersmedicineHumansBipolar disorderDepression (differential diagnoses)RetinaDepressive Disorder Majorbusiness.industryNeurodegenerationGeneral Medicinemedicine.disease030227 psychiatrymedicine.anatomical_structureSchizophreniaOptic nerveSchizophreniaBiomarker (medicine)businessNeuroscience030217 neurology & neurosurgeryTomography Optical CoherenceRevista de psiquiatria y salud mental
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Los cambios estructurales de la retina, ¿nuevos biomarcadores de los trastornos mentales? Una revisión sistemática y síntesis temática de la literatu…

2019

Resumen Recientemente se ha planteado que las alteraciones de las capas de la retina podrian ser un biomarcador de determinados trastornos mentales, al derivar esta de la misma capa embrionaria que el cerebro y estar conectada con este a traves del nervio optico. El objeto del presente articulo es ofrecer una revision sistematica de la literatura y una sintesis tematica sobre el estado actual de las alteraciones de las capas de la retina identificadas mediante tomografia de coherencia optica en los pacientes con esquizofrenia, trastorno bipolar y depresion mayor. Para ello se realizo una busqueda sistematica de la literatura, la lectura critica de los articulos seleccionados y la sintesis t…

03 medical and health sciencesPsychiatry and Mental health0302 clinical medicine030217 neurology & neurosurgery030227 psychiatryRevista de Psiquiatría y Salud Mental
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