0000000000952741

AUTHOR

D Perrone

Il cammino del sole, gli spazi del giorno. Piano urbanistico del comune di Grammichele (CT) su lastra di ardesia dipinta

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Studio diagnostico sul soffitto ligneo dipinto della cattedrale di Nicosia (EN)

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La Grande Guerra racconta sul giornale "L'Ora"

Il saggio propone alcuni momenti ed episodi del primo anno di guerra, attraverso una piccola campionatura di articoli pubblicati sul quotidiano "L’Ora" di Palermo. riguardanti il 1915. Allo scoppio della prima guerra mondiale il quotidiano fondato da Ignazio Florio è al suo quattordicesimo anno di vita ed è sotto la direzione di Francesco Paolo Mulè. Dallo spoglio effettuato emerge che, accanto alla divulgazione dei resoconti ufficiali giunti da Roma, con il quasi quotidiano accompagnamento dei comunicati del Generale Cadorna dal fronte, vengo- no pubblicate corrispondenze di guerra mutuate dal Corriere della sera e del Mattino. Ci si sofferma in particolare su alcuni reportage di Luigi …

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ENDOCANNABINOIDS CB1 AND CB2: A POSSIBLE ROLE IN ORAL SQUAMOUS CELL CARCINOMA PATHOGENESIS

Aim. Cancer of the oral cavity is the eighth most common malignancy in the world. The disease is diagnosed after a considerable delay and predict the individual progression is difficult. The improvements of the therapy did not increased the rate of survival at 5 years, that is still about 50%. The identification of the possible markers that indicates the progression of the tumor is therefore necessary. Endocannabinoids may play an important role in the process of carcinogenesis in the oral mucosa. They are able to bind and activate specific membrane receptors coupled to G proteins, cannabinoid receptors CB1 and CB2. The purpose of this study is to evaluate the expression of CB1 and CB2 rece…

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Indagini multispettrali e termografiche nelle Terme della Rotonda

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La Madonna della Lavina di Cerami: preentazione estetica, osservazione dei materiali di restauro

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Il contributo delle indagini colorimetriche per la conservazione programmata dei mosaici della villa romana del casale di Piazza Armerina (Enna)

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Un’importante decisione:"astice" o "gambero"?Il "Geist der Kochkunst" di Carl F. von Rumohr e "Jenny Treibler" di Theodor Fontane

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Real-time cell analysis by xCELLigence®: a new method for dynamic, quantitative measurement of adhesion and proliferation of cell lines

Objectives. In this study, we report the use of a real-time cell analysis (RTCA) test system, the xCELLigence® RTCA, as efficient tool for a fast growth kinetics analysis of cell lines. This new dynamic real-time monitoring and impedance-based assay allows for a combined measurement of cell adhesion, spreading and proliferation. Methods. We used four representative human OSCC derived cell lines, PE49, HSC2, HSC3 and PE15 cells. The measured impedance values could be correlated to characteristic cell culture behaviours. In parallel, were evaluated proliferation and cell viability of the cell lines by the 3-[4,5-dimethylthizol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) assay. Results. Throug…

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Nell'officina del Gattopardo. Studi sull’opera di Giuseppe Tomasi di Lampedusa

La monografia nasce da una prospettiva di ricerca di gruppo che si è sviluppata poi in un’analisi tematica che ha ricondotto a questioni attinenti alla genesi del romanzo. La ricerca inoltre ricostruisce i termini di un dibattito sul caso Gattopardo di cui si pongono in risalto alcuni snodi cruciali. Quello che vede «L’Ora» di Nisticò chiamare per due volte (nell’anno di pubblicazione del ro- manzo e nel decennale) intellettuali siciliani, e non, a pronunciarsi sul successo del romanzo e, con esso, sul tema della Sicilia su cui si incentrò una delle fondamentali battaglie culturali del quotidiano palermitano. Nella tradizione, dunque, di una scuola, questa monografia, in occasione dei se…

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Gli esordi poetici di Gottfried Benn

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Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with metformin (TOSCA.IT): a randomised, multicentre trial

Background The best treatment option for patients with type 2 diabetes in whom treatment with metformin alone fails to achieve adequate glycaemic control is debated. We aimed to compare the long-term effects of pioglitazone versus sulfonylureas, given in addition to metformin, on cardiovascular events in patients with type 2 diabetes. Methods TOSCA.IT was a multicentre, randomised, pragmatic clinical trial, in which patients aged 50–75 years with type 2 diabetes inadequately controlled with metformin monotherapy (2–3 g per day) were recruited from 57 diabetes clinics in Italy. Patients were randomly assigned (1:1), by permuted blocks randomisation (block size 10), stratified by site and…

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Painful oral aphthous-like lesions in patient with kidney cancer after target therapy and bisphosphonate administration: a case report of adverse drug reaction.

Aim. Tyrosine kinase inhibitors (TKIs) targeting tu- mor angiogenesis and mammalian target of rapamycin inhibitors (mTOR) are indicated for the management of several cancer types, as for renal cell carcinoma (RCC). Oral ulcerations are reported as common adverse drug reactions of mTOR inhibitors and are currently classified as mTOR inhibitor associated stomatitis (mIAS). Interestingly, these lesions appear as aphthous-like stoma- titis rather than the mucositis seen with chemotherapy agent. Case report. A 49 years old male patient underwent to the left radical nephrectomy in May 2014 for clear RCC. From July to October 2014 he was treated with Pazopanib, a tyrosine kinase inhibitor. In Dece…

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Monitoring of the decorative ornaments of the roman villa del casale at Piazza Armerina (Enna)

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Martin Walser, Ein liebender Mann. Rowohlt, Hamburg, 2008

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