FUGARDI M.G. (2008). Dalla condizione di rischio alla prevenzione. In: GIOVANNA PERRICONE, MARIA TERESA DI MAIO E FRANCESCA ROMANA NUCCIO. Raccontando Aladino.. Vincoli e possibilità del lavoro psico-socio-educativo in pediatria. p. 257-265, MILANO: Franco Angeli, ISBN/ISSN: 978-88-464-9807-6

Sonographic monitoring of pelvic organs during pubertal maturation in girls treated for childhood acute leukemia

Abstract Study Objective: To describe pubertal maturation of pelvic organs in long-term female survivors of acute childhood leukemia. Design: A case-control study comparing the uterine and ovarian biometry and the ovarian ultrasonographic patterns. Data were ordered according to age and Tanner staging. Setting: Department of Pediatrics, University of Palermo, Italy. Participants: Department of Obstetrics and Gynecology, Department of Pediatrics, University of Palermo, Italy. Subjects: 11 long-term pubertal female survivors of acute childhood leukemia. 53 healthy pubertal schoolgirls as control group. Interventions: Assessment of pubertal development by Tanner staging and by recording age at…

L'ospedalizzazione pediatrica: colore, parole, fantasia....

Pubertal maturation in girls treated for childhood acute leukaemia.

Eleven girlds treated during childhood for acute leukaemia were followed up during their pubertal development. At each examination weight, height, pubertal stage, FSH, LH, oestradiol, testosterone, androstenedione and dehydroepiandrosterone sulphate levels were evaluated. Clinical and endocrinological studies were performed according to age and pubertal stage and compared to those of healthy girls matched for age and pubertal stage. Results showed that pubertal maturation and gonadal function were not affected by oncotherapy; however menarche was attained earlier. Early menarche was explained by the overweight of treated girls during early puberty. No evidence of early hypothalamic activati…