0000000000954808

AUTHOR

D. Godoy

showing 7 related works from this author

Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across dif…

2017

Background-The usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy of the Framingham-REGICOR scale, validated for the Spanish population, to identify future CVD in participants, who were predefined as being at high-risk in the PREvención con DIeta MEDiterránea (PREDIMED) study-a nutrition-intervention primary prevention trial-and the impact of adherence to the Mediterranean diet on CVD across risk categories. Methods and Results-In a post hoc analysis, we assessed the CVD predictive value of baseline estimated risk in 5966 PREDIMED participants (aged 55-74 years, 57% women; 48% with type 2 diabetes mellitus). Major …

MaleMediterranean dietEpidemiologyDisease030204 cardiovascular system & hematologyDiet MediterraneanCohort Studies0302 clinical medicineRisk FactorsMedicine030212 general & internal medicineRisk assessmentOriginal ResearchDiet and NutritionAged 80 and overFramingham Risk ScoreDiabetisDiabetesMiddle AgedPrognosisCardiovascular diseasePrimary PreventionCardiovascular diseasesCardiovascular DiseasesCohortFemaleCardiology and Cardiovascular MedicineFramingham‐REGICOR equationPREDIMEDCardiovascular risk predictionScale (ratio)Risk Assessment03 medical and health sciencesMediterranean dietHumanscardiovascular diseasesAgedProportional Hazards ModelsFramingham-REGICOR equationbusiness.industryMalalties cardiovascularsFeeding BehaviorLifestylePredimedDiabetes Mellitus Type 2SpainAvaluació del riscMediterraneam dietbusinessDemography
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Obese Subjects Carrying the 11482G>A Polymorphism at the Perilipin Locus Are Resistant to Weight Loss after Dietary Energy Restriction

2005

Dietary treatment of obesity could be improved if predictive information about the individual's genetic response to diet was available. Adipose tissue has been the focus of efforts to identify candidate genes. Perilipin is a major protein found in adipocytes, and perilipin knockout mice are lean and resistant to diet-induced obesity.The objective of the study was to examine the association of several polymorphisms at the perilipin (PLIN) locus with obesity and weight reduction in response to a low-energy diet in obese patients.This study was a 1-yr randomized (depending on the PLIN genotype) trial with three follow-up evaluations.The study was conducted at a university research center.One h…

AdultMaleHeterozygotePerilipin-1medicine.medical_specialtyCandidate geneGuanineEndocrinology Diabetes and MetabolismClinical BiochemistryAdipose tissueBiologyBiochemistryEndocrinologyWeight lossInternal medicineWeight LossGenotypePrevalencemedicineHumansObesityAlleleAllelesAgedCaloric RestrictionPolymorphism GeneticAdenineBiochemistry (medical)Middle AgedPhosphoproteinsmedicine.diseaseObesityEndocrinologyDiabetes Mellitus Type 2PerilipinFemalemedicine.symptomCarrier ProteinsBody mass indexThe Journal of Clinical Endocrinology & Metabolism
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Genetic variation at the perilipin (PLIN) locus is associated with obesity-related phenotypes in White women

2004

Perilipin coats intracellular lipid droplets and modulates adipocyte lipolysis. We have evaluated the association between several polymorphisms at the perilipin (PLIN) locus (PLIN1 : 6209T > C, PLIN4 : 11482G > A, PLIN5 : 13041A > G, and PLIN6 : 14995A > T) with obesity-related phenotypes in 1589 White subjects randomly selected from a general Spanish population. In women (n = 801), the less common alleles of PLIN1 and PLIN4, in strong linkage disequilibrium (D' : 0.96), were significantly associated with lower body mass index. Carriers of the allele 2 (6209C) at the PLIN1 locus weighed significantly less (-2.2 kg; p = 0.007) than women homozygotes for the wild-type genotype. The same was t…

medicine.medical_specialtyLinkage disequilibriumLocus (genetics)Odds ratioBiologymedicine.diseaseObesityEndocrinologyInternal medicineGenotypeGeneticsPerilipinmedicineAlleleBody mass indexGenetics (clinical)Clinical Genetics
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Legume consumption is inversely associated with type 2 diabetes incidence in adults: A prospective assessment from the PREDIMED study

2018

Background & aims: Legumes, a low-energy, nutrient-dense and low glycemic index food, have shown beneficial effects on glycemic control and adiposity. As such, legumes are widely recommended in diabetic diets, even though there is little evidence that their consumption protects against type 2 diabetes. Therefore the aim of the present study was to examine the associations between consumption of total legumes and specific subtypes, and type 2 diabetes risk. We also investigated the effect of theoretically substituting legumes for other protein- or carbohydrate-rich foods. Methods: Prospective assessment of 3349 participants in the PREvención con DIeta MEDiterránea (PREDIMED) study without ty…

0301 basic medicineGerontologyBlood GlucoseMaleLentilsMediterranean dietPREDIMED-study030209 endocrinology & metabolismContext (language use)Type 2 diabetesCritical Care and Intensive Care MedicineLower riskDiet Mediterranean03 medical and health sciences0302 clinical medicineRisk FactorsDiabetes mellitusmedicineHumansProspective StudiesGlycemicAdiposityAgedProportional Hazards Models030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industryFabaceaeType 2 diabetesMiddle Agedmedicine.diseaseLegumesDietGlycemic indexQuartileDiabetes Mellitus Type 2Glycemic IndexFemalebusinessDemographyFollow-Up Studies
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Dietary inflammatory index and all-cause mortality in large cohorts: The SUN and PREDIMED studies

2019

[Background]: Inflammation is known to be related to the leading causes of death including cardiovascular disease, several types of cancer, obesity, type 2 diabetes, depression-suicide and other chronic diseases. In the context of whole dietary patterns, the Dietary Inflammatory Index (DII®) was developed to appraise the inflammatory potential of the diet. [Objective]: We prospectively assessed the association between DII scores and all-cause mortality in two large Spanish cohorts and valuated the consistency of findings across these two cohorts and results published based on other cohorts.

AdultMale0301 basic medicinemedicine.medical_specialtyMediterranean diet030209 endocrinology & metabolismContext (language use)Type 2 diabetesDiet MediterraneanCritical Care and Intensive Care MedicineDietary inflammatory indexBody Mass IndexYoung Adult03 medical and health sciences0302 clinical medicineRisk FactorsInternal medicineMediterranean dietHumansMedicineObesityProspective StudiesMortalityProspective cohort studyRandomized Controlled Trials as TopicInflammation030109 nutrition & dieteticsNutrition and Dieteticsbusiness.industrySmokingHazard ratioMiddle Agedmedicine.diseaseObesityDietC-Reactive ProteinDiabetes Mellitus Type 2CohortPatient ComplianceCohort studiesFemalebusinessCRPCohort study
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Potato consumption does not increase blood pressure or incident hypertension in 2 cohorts of Spanish adults

2017

5 Tablas

AdultMalePediatricsmedicine.medical_specialtyDiastoleMedicine (miscellaneous)030204 cardiovascular system & hematologyMediterranean03 medical and health sciences0302 clinical medicineAnimal scienceGlycemic loadSUN cohortmedicineHumans030212 general & internal medicineIntervention trialProspective cohort studyPotatoesGeneralized estimating equationAgedSolanum tuberosumAged 80 and overNutrition and DieteticsIncrease blood pressurebusiness.industryIncidence (epidemiology)PREDIMED studyMiddle AgedDietBlood pressureSpainHypertensionBlood pressureFemalebusiness
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Dietary α-Linolenic Acid, Marine ω-3 Fatty Acids, and Mortality in a Population With High Fish Consumption: Findings From the PREvención con DIeta ME…

2016

12 Páginas.-- 6 Tablas.-- 1 Figura

MaleGerontologyTime FactorsEpidemiologymodelos de riesgos proporcionaleshumanos030204 cardiovascular system & hematologychemistry.chemical_compound0302 clinical medicineRisk Factorsestudios prospectivosevaluación de riesgosMedicineNutsSudden cardian death030212 general & internal medicineFood scienceLongitudinal StudiesProspective Studiesmediana edadOriginal ResearchDiet and NutritionAged 80 and overchemistry.chemical_classificationeducation.field_of_studyancianoalpha-Linolenic aciddietaFactors de risc en les malaltiesHàbits alimentarisFatty Acidsω-3 fatty acidsFatty acids in human nutritionalpha-Linolenic Aciddistribución de la ji al cuadradoMiddle AgedCardiovascular systemnutritionCardiovascular DiseasesFemaleDietaCardiology and Cardiovascular MedicineNutritive Valueconducta de reducción del riesgoRisk factors in diseasesFood habitsPopulationenfermedades cardiovasculares030209 endocrinology & metabolismJuglansRisk Assessmentsudden cardiac death03 medical and health sciencesalimentos del marfactores de tiempoMediterranean cookingÀcids grassos en la nutricióFatty Acids Omega-3Cuina mediterràniaPeix com a alimentHumansfactores de riesgoanálisis multifactorialeducationOlive OilDieta -- Mediterrània Regió de laDieta mediterraneaácidos grasosα-linolenic acidAgedProportional Hazards ModelsSistema cardiovascularChi-Square Distributionbusiness.industryCorrectionFatty acidHàbits alimentaris -- Mediterrània Regió de laProtective FactorsFish consumptionPredimedDietnueceschemistrySeafoodSpainMultivariate Analysisvalor nutritivoestudios longitudinalesfatty acidbusinessRisk Reduction Behaviorácido alfa-linolénico
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