0000000000959616

AUTHOR

A. Lange

showing 8 related works from this author

'Immunogenetics of Aging': report on the activities of the 15th International HLA and Immunogenetics Working Group and 15th International HLA and Imm…

2011

'Immunogenetics of Aging' is a component that was first included in the 14th International HLA and Immunogenetics Workshop (IHIWS) and developed further within the 15th Workshop. The aim of this component was to assess the impact of human leukocyte antigen (HLA) genes, cytokine genes, and some innate immunity genes such as killer-cell immunoglobulin-like receptors (KIRs) and mannose-binding lectin 2 (MBL2) in successful aging and their contribution to the better understanding of immune dysfunction in old age. Within the 15th IHIWS new populations were included in the analysis. Additional cytokine gene polymorphisms were assessed and innate immunity genes were analyzed for possible relevance…

aging; cytokine gene polymorphism; killer-cell immunoglobulin-like receptor genes; longevity; mannose-binding lectin 2 geneGeneticsInnate immune systemSuccessful agingkiller-cell immunoglobulin-like receptor genemedia_common.quotation_subjectImmunologyHaplotypeagingLongevityKILLER-CELL IMMUNOGLOBULIN-LIKE RECEPTOR GENESGeneral MedicineImmunogeneticsHuman leukocyte antigenBiologyCytokine gene polymorphismmannose-binding lectin 2 geneBiochemistryImmune systemImmunologyGeneticsImmunology and AllergyLONGEVITYGenemedia_common
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Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

2018

Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those…

MaleOriginalEpidemiology[SDV]Life Sciences [q-bio]HSJ UCIlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]MULTICENTERclinical outcomemortality rateCritical Care and Intensive Care Medicineintensive care unitlaw.invention0302 clinical medicineSeverity of diseaselawEpidemiologymiddle agedMedicine and Health SciencesFAILURE030212 general & internal medicineHospital Mortalityintensive care units -- analysis -- epidemiology -- mortalityGeneralLiterature_REFERENCE(e.g.dictionariesencyclopediasglossaries)CODEScomparative studyintensive careMedicine(all)multilevel analysiIncidenceadultSciences bio-médicales et agricolesIntensive care unit3. Good healthEuropesepsaIntensive Care UnitsfemaleCohortenote intenzivne terapije -- analiza -- epidemiologija -- umrljivostHumanAdultmedicine.medical_specialtyseverity of diseaseCritical CareSepsiIntensive Care UnitUNITED-STATES610 Medicine & healthINTENSIVE-CAREEuropeanArticleSepsisEpidemiology; Sepsis; Severity of disease03 medical and health sciencesAll institutes and research themes of the Radboud University Medical Centerlength of staymaleEpidemiology; Sepsis; Severity of disease; Adult; Europe; Hospital Mortality; Humans; Length of Stay; Male; Critical Care; Intensive Care Units; SepsisAnesthesiologyIntensive careSepsisSCOREmedicineudc:614.2Humanshumanoutcome assessmentSeptic shockbusiness.industrySEPTIC SHOCK030208 emergency & critical care medicineLength of Staymedicine.diseaseTRENDSmajor clinical studySEVERE SEPSIScomorbidity assessmentEmergency medicineEpidemiology; Sepsis; Severity of disease; Critical Care and Intensive Care MedicineObservational studyCLAIMSbusinessSepsis;Severity of disease;Epidemiologyresnost bolezni
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Erratum to: The Intensive Care Global Study on Severe Acute Respiratory Infection (IC‑GLOSSARI): a multicenter, multinational, 14-day inception coh…

2018

In both the original publication (DOI 10.1007/s00134-015-4206-2) and the first erratum (DOI 10.1007/s00134-016-4317-4), the members of the IC-GLOSSARI Investigators and the ESICM Trials Group were provided in such a way that they could not be indexed as collaborators on PubMed. The publisher apologizes for these errors and is pleased to list the members of the groups here: (Table presented.).

Critical Care and Intensive Care Medicine
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16th IHIW: Immunogenetics of Aging

2013

Ageing is a process characterised by progressive loss of function in multiple different organ systems, such as the nervous, endocrine and immune systems. Current data showing that ageing processes may be associated with alterations in the immune system suggest that some of the genetic determinants of senescence might be polymorphic genes that regulate immune responses. The ‘Immunogenetics of Aging’ programme was a component introduced in the 14th International HLA and Immunogenetics Workshop (IHIWS) and developed further within the 15th and 16th. The aim of this component was to determine the contribution of immune genes to successful ageing and an increased capacity to reach the extreme li…

Settore MED/04 - Patologia GeneraleLongevity immunogenetics genetics
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Assessment of the worldwide burden of critical illness: The Intensive Care Over Nations (ICON) audit

2014

Item does not contain fulltext BACKGROUND: Global epidemiological data regarding outcomes for patients in intensive care units (ICUs) are scarce, but are important in understanding the worldwide burden of critical illness. We, therefore, did an international audit of ICU patients worldwide and assessed variations between hospitals and countries in terms of ICU mortality. METHODS: 730 participating centres in 84 countries prospectively collected data on all adult (>16 years) patients admitted to their ICU between May 8 and May 18, 2012, except those admitted for fewer than 24 h for routine postoperative monitoring. Participation was voluntary. Data were collected daily for a maximum of 28 da…

Pulmonary and Respiratory Medicinemedicine.medical_specialtyCritical Illnesshealth care facilities manpower and servicesPopulationlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Critical care european intensive care icon studyComorbidityintensive care medicineGlobal HealthMOF; sepsis; critically ill[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tractICON Intensive CareArticleSepsisCohort StudiesOutcome Assessment (Health Care)Intensive careSepsisOutcome Assessment Health CareEpidemiologyHealth careSettore MED/41 - ANESTESIOLOGIAmedicineGlobal healthcritical illness mortalityHumansHospital MortalityeducationIntensive care medicineeducation.field_of_studyMedical Auditbusiness.industryIntensive Caremedicine.diseaseComorbidity3. Good healthIntensive Care UnitsICONbusinessCohort study
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CCDC 290684: Experimental Crystal Structure Determination

2006

Related Article: A.Lange, M.M.Kubicki, J.Wachter, M.Zabel|2005|Inorg.Chem.|44|7328|doi:10.1021/ic050493e

Space GroupCrystallographyCrystal SystemCrystal Structuretris(mu~3~-sulfido)-(mu~2~-sulfido)-tris(eta^5^-pentamethylcyclopentadienyl)-di-antimony-tri-rhodium sulfide tetrahydrofuran solvateCell ParametersExperimental 3D Coordinates
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CCDC 200715: Experimental Crystal Structure Determination

2003

Related Article: H.Brunner, M.M.Kubicki, A.Lange, J.Wachter, E.Vigier, M.Zabel|2003|Angew.Chem.,Int.Ed.|42|3547|doi:10.1002/anie.200350931

Space GroupCrystallography(mu~2~-Stibinosulfide-SSSbSb)-tetracarbonyl-bis(eta^5^-pentamethylcyclopentadienyl)-di-molybdenum hexafluorophosphate tetrahydrofuran solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 290685: Experimental Crystal Structure Determination

2006

Related Article: A.Lange, M.M.Kubicki, J.Wachter, M.Zabel|2005|Inorg.Chem.|44|7328|doi:10.1021/ic050493e

Space GroupCrystallography(mu~3~-disulfido)-tris(mu~3~-sulfido)-tetrakis((eta^5^-pentamethylcyclopentadienyl)-rhodium) toluene solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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