Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

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RESEARCH PRODUCT

Comparison of European ICU patients in 2012 (ICON) versus 2002 (SOAP)

J. -L. Vincent J. -Y. Lefrant K. Kotfis R. Nanchal I. Martin-loeches X. Wittebole S. G. Sakka P. Pickkers R. Moreno Y. Sakr P. Pavlik J. Manak E. Kieslichova R. Turek M. Fischer R. Valkova L. Dadak P. Dostal J. Malaska R. Hajek A. ŽIdková P. Lavicka L. Medve A. Sarkany I. Kremer Z. Marjanek P. Tamasi J. Kolbusz A. Kübler B. Mielczarek M. Mikaszewska-sokolewicz K. Kotfis B. Tamowicz W. Sulkowski P. Smuszkiewicz A. Pihowicz E. Trejnowska N. Hagau D. Filipescu G. Droc M. Lupu A. Nica R. Stoica D. Tomescu D. Constantinescu G. Valcoreanu Zbaganu A. Slavcovici L. Soskic I. Palibrk R. Jankovic B. Jovanovic M. Pandurovic V. Bumbasirevic B. Uljarevic M. Surbatovic N. Ladjevic G. Slobodianiuk V. Sobona A. Cikova A. Gebhardtova J. Cohen O. Sold P. Urbanek J. Schlieber J. Reisinger J. Auer A. Hartjes A. Lerche T. Janous E. Kink W. Krahulec K. Smolle M. Van Der Schueren P. Thibo M. Vanhoof I. Ahmet G. Philippe P. Dufaye O. Jacobs V. Fraipont P. Biston A. Dive Y. Bouckaert E. Gilbert B. Gressens E. Pinck V. Collin J. L. Vincent J. De Waele R. Rimachi D. Gusu K. De Decker K. Mandianga L. Heytens X. Wittebole S. Herbert V. Olivier W. Vandenheede P. Rogiers P. Kolodzeike M. Kruse T. Andersen V. Harjola K. Saarinen M. Leone A. Durocher S. Moulront A. Lepape M. Losser P. Cabaret E. Kalaitzis E. Zogheib P. Charve B. Francois J. Y. Lefrant B. Beilouny X. Forceville B. Misset F. Jacobs F. Bernard D. Payen A. Wynckel V. Castelain A. Faure P. Lavagne L. Thierry M. Moussa A. Vieillard-baron M. Durand M. Gainnier C. Ichai S. Arens C. Hoffmann M. Kaffarnik C. Scharnofske I. Voigt C. Peckelsen M. Weber J. Gille A. Lange G. Schoser A. Sablotzki U. Jaschinski A. Bluethgen F. Vogel A. Tscheu T. Fuchs M. Wattenberg T. Helmes S. Scieszka M. Heintz S. Sakka J. Kohler F. Fiedler M. Danz Y. Sakr R. Riessen T. Kerz A. Kersten F. Tacke G. Marx T. Volkert A. Schmutz A. Nierhaus S. Kluge P. Abel R. Janosi S. Utzolino H. Bracht S. Toussaint M. Giannakou Peftoulidou P. Myrianthefs A. Armaganidis C. Routsi A. Xini E. Mouloudi I. Kokoris G. Kyriazopoulos S. Vlachos A. Lavrentieva P. Partala G. Nakos J. Barry R. O’leary C. Motherway M. Faheem E. Dunne M. Donnelly T. Konrad E. Bonora C. Achilli S. Rossi G. Castiglione A. Peris D. Albanese N. Stocchetti G. Citerio L. Mozzoni E. Sisillo P. De Negri M. Savioli P. Vecchiarelli F. Puflea V. Stankovic G. Minoja S. Montibeller P. Calligaro R. Sorrentino M. Feri M. Zambon E. Colombaroli A. Giarratano T. Pellis C. Capra M. Antonelli A. Gullo C. Chelazzi A. De Capraris N. Patroniti M. Girardis F. Franchi G. Berlot H. Ponssen J. Ten Cate L. Bormans S. Husada M. Buise B. Van Der Hoven A. Reidinga M. Kuiper P. Pickkers G. Kluge S. Den Boer J. Kesecioglu H. Van Leeuwen H. Flaatten S. Mo V. Branco F. Rua E. Lafuente M. Sousa N. Catorze M. Barros L. Pereira A. Vintém De Oliveira J. Gomes I. Gaspar M. Pereira M. Cymbron A. Dias E. Almeida S. Beirao I. Serra R. Ribeiro P. Povoa F. Faria Z. Costa-e-silva J. Nóbrega F. Fernandes J. Gabriel G. Voga E. Rupnik L. Kosec M. Kerin Povšic I. Osojnik V. Tomic A. Sinkovic J. González E. Zavala J. Pérez Valenzuela L. Marina P. Vidal-cortés P. Posada A. Ignacio Martin-loeches N. Muñoz Guillén M. Palomar J. Sole-violan A. Torres M. Gonzalez Gallego G. Aguilar R. Montoiro Allué M. Argüeso M. Parejo M. Palomo Navarro A. Jose N. Nin F. Alvarez Lerma O. Martinez E. Tenza Lozano S. Arenal López M. Perez Granda S. Moreno C. Llubia C. De La Fuente Martos P. Gonzalez-arenas N. Llamas Fernández B. Gil Rueda I. Estruch Pons N. Cruza F. Maroto A. Estella A. Ferrer L. Iglesias Fraile B. Quindos A. Quintano M. Tebar P. Cardinal A. Reyes A. Rodríguez A. Abella S. García Del Valle S. Yus E. Maseda J. Berezo A. Tejero Pedregosa C. Laplaza R. Ferrer J. Rico-feijoo M. Rodríguez P. Monedero K. Eriksson D. Lind D. Chabanel H. Zender K. Heer B. Frankenberger S. Jakob A. Haller S. Mathew R. Downes C. Barrera Groba A. Johnston R. Meacher R. Keays P. Haji-michael C. Tyler A. Ferguson S. Jones D. Tyl A. Ball J. Vogel M. Booth P. Downie M. Watters S. Brett M. Garfield L. Everett S. Heenen S. Dhir Z. Beardow M. Mostert S. Brosnan N. Pinto S. Harris A. Summors N. Andrew A. Rose R. Appelboam O. Davies E. Vickers B. Agarwal T. Szakmany S. Wimbush I. Welters R. Pearse R. Hollands J. Kirk-bayley N. Fletcher B. Bray D. Brealey G. Delle Karth V. Draxler G. Filzwieser W. Heindl G. Kellner K. Lenz E. Rossmann C. Wiedermann P. Biston D. Chochrad V. Collin P. Damas J. Decruyenaere E. Hoste J. Devriendt B. Espeel V. Fraipont E. Installe M. Malbrain G. Nollet J. C. Preiser J. Raemaekers A. Roman M. Simon H. Spapen W. Swinnen F. Vallot J. L. Vincent I. Chytra L. Dadak I. Herold F. Polak M. Sterba M. Bestle K. Espersen H. Guldager K. -L. Welling D. Nyman E. Ruokonen K. Saarinen D. Annane P. Catogni G. Colas F. Coulomb R. Dorne M. Garrouste C. Isetta J. Larché J. -R. Legall H. Lessire Y. Malledant P. Mateu M. Ossart D. Payen P. Schlossmacher J. -F. Timsit S. Winnock J. -P. Sollet L. Mallet P. Maurer J. M. Sab J. P. Sollet G. Aykut F. Brunkhorst A. Nierhaus M. Lauterbach M. Ragaller R. Gatz H. Gerlach D. Henzler H. -B. Hopf H. Hueneburg W. Karzai A. Keller T. Bauer U. Kuhlmann J. Langgartner C. Manhold M. Ragaller B. Reith T. Schuerholz C. Spies R. Stögbauer J. Unterburger P. -M. Clouva-molyvdas G. Giokas E. Ioannidou A. Lahana A. Liolios K. Marathias G. Nakos A. Tasiou H. Tsangaris P. Tamasi B. Marsh M. Power C. Sprung B. Biagioli F. Bobbio Pallavicini A. Pesenti C. Capra F. Della Corte P. P. Donadio A. Donati A. Giarratano T. Giorgio D. Giudici S. Greco A. Guadagnucci G. Lapichino S. Livigni G. Moise G. Nardi E. Panascia M. Pizzamiglio V. M. Ranieri R. Rosi A. Sicignano M. Solca G. Vignali I. Volpe Rinonapoli M. Barnas E. E. De Bel A. -C. De Pont J. Groeneveld M. Nijsten L. Sie D. F. Zandstra S. Harboe S. Lindén R. Z. Lovstad H. Moen N. Smith-erichsen A. Piotrowski E. Karpel E. Almeida R. Moreno A. Pais-de-lacerda J. A. Paiva I. Serra A. Pimentel D. Filipescu K. Jovanovic P. Malik K. Lucka G. Voga C. Aldecoa Alvarez-santullano A. Artigas E. Zavala A. Escorsell J. Nicolas J. J. Izura Cea L. Marina J. Montejo E. Palencia F. Santos R. Sierra-camerino F. Sipmann E. Zavala K. Brodersen J. Haggqvist D. Hermansson H. Hjelmqvist K. Heer G. Loderer M. Maggiorini H. Zender P. Andrews B. Appadu C. Barrera Groba J. Bewley K. Burchett P. Chambers J. Coakley D. Doberenz N. Eastwood A. Ferguson J. Fielden J. Gedney K. Gunning D. Harling S. Jankowski D. Jayson A. Kilner V. Krishna-kumar K. Lei S. Mackenzie P. Macnaughton G. Marx C. Mcculloch P. Morgan A. Rhodes C. Roberts M. Russell D. Tupper-carey M. Wright L. Twohey J. Watts R. Webster D. Williams On Behalf Of The Icon And Soap Investigators And Soap Investigators

subject

Male Original Epidemiology [SDV]Life Sciences [q-bio]HSJ UCI lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]MULTICENTER clinical outcome mortality rate Critical Care and Intensive Care Medicine intensive care unit law.invention 0302 clinical medicine Severity of disease law Epidemiology middle aged Medicine and Health Sciences FAILURE 030212 general & internal medicine Hospital Mortality intensive care units -- analysis -- epidemiology -- mortality GeneralLiterature_REFERENCE(e.g.dictionaries encyclopedias glossaries)CODES comparative study intensive care Medicine(all)multilevel analysi Incidence adult Sciences bio-médicales et agricoles Intensive care unit 3. Good health Europe sepsa Intensive Care Units female Cohort enote intenzivne terapije -- analiza -- epidemiologija -- umrljivost Human Adult medicine.medical_specialty severity of disease Critical Care Sepsi Intensive Care Unit UNITED-STATES 610 Medicine & health INTENSIVE-CARE European Article Sepsis Epidemiology; Sepsis; Severity of disease 03 medical and health sciences All institutes and research themes of the Radboud University Medical Center length of stay male Epidemiology; Sepsis; Severity of disease; Adult; Europe; Hospital Mortality; Humans; Length of Stay; Male; Critical Care; Intensive Care Units; Sepsis Anesthesiology Intensive care Sepsis SCORE medicine udc:614.2 Humans human outcome assessment Septic shock business.industry SEPTIC SHOCK 030208 emergency & critical care medicine Length of Stay medicine.disease TRENDS major clinical study SEVERE SEPSIS comorbidity assessment Emergency medicine Epidemiology; Sepsis; Severity of disease; Critical Care and Intensive Care Medicine Observational study CLAIMS business Sepsis;Severity of disease;Epidemiology resnost bolezni

description

Purpose: To evaluate differences in the characteristics and outcomes of intensive care unit (ICU) patients over time. Methods: We reviewed all epidemiological data, including comorbidities, types and severity of organ failure, interventions, lengths of stay and outcome, for patients from the Sepsis Occurrence in Acutely ill Patients (SOAP) study, an observational study conducted in European intensive care units in 2002, and the Intensive Care Over Nations (ICON) audit, a survey of intensive care unit patients conducted in 2012. Results: We compared the 3147 patients from the SOAP study with the 4852 patients from the ICON audit admitted to intensive care units in the same countries as those in the SOAP study. The ICON patients were older (62.5 ± 17.0 vs. 60.6 ± 17.4 years) and had higher severity scores than the SOAP patients. The proportion of patients with sepsis at any time during the intensive care unit stay was slightly higher in the ICON study (31.9 vs. 29.6%, p = 0.03). In multilevel analysis, the adjusted odds of ICU mortality were significantly lower for ICON patients than for SOAP patients, particularly in patients with sepsis [OR 0.45 (0.35–0.59), p < 0.001]. Conclusions: Over the 10-year period between 2002 and 2012, the proportion of patients with sepsis admitted to European ICUs remained relatively stable, but the severity of disease increased. In multilevel analysis, the odds of ICU mortality were lower in our 2012 cohort compared to our 2002 cohort, particularly in patients with sepsis.

year	journal	country	edition	language
2018-02-15

10.1007/s00134-017-5043-2 http://hdl.handle.net/11585/667216