0000000000960915
AUTHOR
M. Van Dijk
Imaging and biochemical biomarkers of psychiatric comorbidities in a rat epilepsy model
Aims: Biomarkers of epilepsy-associated psychiatric comorbidities represent a powerful tool for an early diagnosis and personalized therapy in patients with epilepsy. Here, in order to identify new candidates as biomarkers of epilepsy comorbidities, alterations in brain metabolic activity and serotonergic neurotransmission in a rat post-status epilepticus model were explored and cross-correlated with alterations in various neurobehavioral and biochemical parameters. Methods: Status epilepticus was induced in twelve female Sprague Dawley rats by lithium chloride-pilocarpine treatment. µPET analysis to determine [18F]FDG uptake and [18F]MPPF binding were performed in the chronic phase of epil…
The “Physics Beyond Colliders” Projects for the CERN M2 Beam
Abstract Physics Beyond Colliders is an exploratory study aimed at exploiting the full scientific potential of CERN’s accelerator complex up to 2040 and its scientific infrastructure through projects complementary to the existing and possible future colliders. Within the Conventional Beam Working Group (CBWG), several projects for the M2 beam line in the CERN North Area were proposed, such as a successor for the COMPASS experiment, a muon programme for NA64 dark sector physics, and the MuonE proposal aiming at investigating the hadronic contribution to the vacuum polarisation. We present integration and beam optics studies for 100 – 160 GeV/c muon beams as well as an outlook for improvement…
Measurements of the Λb0→J/ψΛ decay amplitudes and the Λb0 polarisation in pp collisions at s=7 TeV
An angular analysis of Λ0b→J/ψΛ decays is performed using a data sample corresponding to 1.0 fb−1 collected in pp collisions at √s=7 TeV with the LHCb detector at the LHC. A parity violating asymmetry parameter characterising the Λ0b→J/ψΛ decay of 0.05±0.17±0.07 and a Λ0b transverse production polarisation of 0.06±0.07±0.02 are measured, where the first uncertainty is statistical and the second systematic.
Searches for violation of lepton flavour and baryon number in tau lepton decays at LHCb
Searches for the lepton flavour violating decay tau(-) -> mu(-)mu(+)mu(-) and the lepton flavour and baryon number violating decays tau(-) -> (p) over bar mu(+)mu(-) and tau(-) -> p mu(-)mu(-) have been carried out using proton-proton collision data, corresponding to an integrated luminosity of 1.0 fb(-1), taken by the LHCb experiment at root s = 7 TeV. No evidence has been found for any signal, and limits have been set at 90% confidence level on the branching fractions: B(tau(-) -> mu(-)mu(+)mu(-) mu(+)mu(-)) p mu(-)mu(-)) (p) over bar mu(+)mu(-) and tau(-) -> p mu(-)mu(-) decay modes represent the first direct experimental limits on these channels.
Observation of the suppressed ADS modes B±→[π±K∓π+π−]DK± and B±→[π±K∓π+π−]Dπ±
An analysis of and B-+/- -> DK +/- and B-+/- -> D pi(+/-) decays is presented where the D meson is reconstructed in the four-body final state K-+/-pi(-/+)pi(+)pi(-). Using LHCb data corresponding to an integrated luminosity of 1.0 fb(-1), first observations are made of the suppressed ADS modes B-+/- ->[pi K-+/-(-/+)pi(+)pi(-)](D)K-+/- and B +/- -> [pi K-+/-(-/+)pi(+)pi(-)](D)pi(+/-) with a significance of 5.1 sigma and greater than 10 sigma, respectively. Measurements of CP asymmetries and CP-conserving ratios of partial widths from this family of decays are also performed. The magnitude of the ratio between the suppressed and favoured B-+/- -> DK +/- amplitudes is determined to be r(B)(K) …